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21928-51-8

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21928-51-8 Usage

Description

5-Bromo-1,2,3-trichlorobenzene is an organic compound that features a benzene ring with one bromine atom and three chlorine atoms attached to it. It is a synthetic chemical used as an intermediate in various chemical reactions and has applications in the pharmaceutical and agrochemical industries.

Uses

Used in Pharmaceutical Industry:
5-Bromo-1,2,3-trichlorobenzene is used as a pharmaceutical intermediate for the synthesis of various drugs. Its unique structure allows it to be a key component in the development of new medications, contributing to the advancement of pharmaceutical research and drug discovery.
Used in Agrochemical Industry:
5-Bromo-1,2,3-trichlorobenzene is used as an intermediate in the preparation of isoxazole derivatives, which are effective in controlling parasites such as Rhipicephalus sanguineous nymphs. These derivatives play a crucial role in the development of new pesticides and other agrochemical products to protect crops and livestock from harmful parasites.

Check Digit Verification of cas no

The CAS Registry Mumber 21928-51-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,9,2 and 8 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 21928-51:
(7*2)+(6*1)+(5*9)+(4*2)+(3*8)+(2*5)+(1*1)=108
108 % 10 = 8
So 21928-51-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H2BrCl3/c7-3-1-4(8)6(10)5(9)2-3/h1-2H

21928-51-8 Well-known Company Product Price

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  • (Code)Product description
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  • Alfa Aesar

  • (H64506)  1-Bromo-3,4,5-trichlorobenzene, 98%   

  • 21928-51-8

  • 5g

  • 245.0CNY

  • Detail
  • Alfa Aesar

  • (H64506)  1-Bromo-3,4,5-trichlorobenzene, 98%   

  • 21928-51-8

  • 25g

  • 951.0CNY

  • Detail
  • Alfa Aesar

  • (H64506)  1-Bromo-3,4,5-trichlorobenzene, 98%   

  • 21928-51-8

  • 100g

  • 3107.0CNY

  • Detail

21928-51-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Bromo-1,2,3-trichlorobenzene

1.2 Other means of identification

Product number -
Other names 3,4,5-TRICHLOROBROMOBENZENE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:21928-51-8 SDS

21928-51-8Relevant articles and documents

Preparation method of halogenated trifluoroacetyl benzene

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Paragraph 0092-0103, (2021/06/02)

The invention relates to the field of organic synthesis, in particular to a preparation method of halogenated trifluoroacetyl benzene. The invention provides a preparation method of 3,4,5-trichlorotrifluoroacetyl benzene on the first aspect, which comprises the following steps: 1) carrying out diazotization and chlorination reaction on 2,6-dichloro-4-bromoaniline to provide 3,4,5-trichlorobromobenzene; (2) carrying out Grignard reaction on the 3,4,5-trichlorobromobenzene so as to provide 3,4,5-trichlorophenyl magnesium bromide; and 3) carrying out a trifluoroacetylation reaction on the 3,4,5-trichlorophenyl magnesium bromide and a trifluoroacetylation reagent, so as to provide the 3,4,5-trichlorotrifluoroacetyl benzene. According to the preparation method of 3,4,5-trichlorotrifluoroacetyl benzene, provided by the invention, 2,6-dichloro-4-bromoaniline is adopted as a raw material, a target product is prepared through a diazotization reaction, a Grignard reaction and a trifluoroacetylation reaction, the whole preparation route is simple in reaction step operation, the product is easy to purify, the yield is high, and the preparation method is very suitable for large-scale production; and the method has a good industrialization prospect.

PROCESS FOR THE PREPARATION OF 5-BROMO-1,2,3-TRICHLOROBENZENE

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Page/Page column 5, (2016/05/24)

The present invention relates to a process for the preparation of a compound of formula I (I), comprising reacting a compound of formula II (II), with a brominating agent in the presence of an acidic catalyst to a compound of formula III (III), and reacti

Catalytic Sandmeyer bromination

Beletskaya, Irina P.,Sigeev, Alexander S.,Peregudov, Alexander S.,Petrovskii, Pavel V.

, p. 2534 - 2538 (2008/03/13)

An efficient catalyst system for Sandmeyer bromination is proposed. Aryl bromides and dibromides can be obtained with excellent yield by this synthetic protocol. Georg Thieme Verlag Stuttgart.

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