21703-08-2

Basic information

• Product Name: 1-(3 4-DICHLOROPHENYL)BIGUANIDE HYDROC&
• Synonyms: 1-(3 4-DICHLOROPHENYL)BIGUANIDE HYDROC&;{[(3,4-dichloroanilino)(imino)methyl]amino}methanimidamide hydrochloride;Nsc526876;N-(3,4-Dichlorophenyl)imidodicarbonimidic diamide hydrochloride
• CAS NO: 21703-08-2
• Molecular Formula: C₈H₉Cl₂N₅*ClH
• Molecular Weight: 282.56
• Product Categories: Guanidines;Nitrogen Compounds;Organic Building Blocks
• Mol File: 21703-08-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 222-228 °C(lit.)
• Boiling Point: 470.9°C at 760 mmHg
• Flash Point: 238.6°C
• Appearance: /
• Vapor Pressure: 4.89E-09mmHg at 25°C
• CAS DataBase Reference: 1-(3 4-DICHLOROPHENYL)BIGUANIDE HYDROC&(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3 4-DICHLOROPHENYL)BIGUANIDE HYDROC&(21703-08-2)
• EPA Substance Registry System: 1-(3 4-DICHLOROPHENYL)BIGUANIDE HYDROC&(21703-08-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 21703-08-2(Hazardous Substances Data)

Usage

Description

1-(3 4-Dichlorophenyl)biguanide hydrochloride is a chemical compound with antimicrobial properties, commonly used as an antiseptic and disinfectant in pharmaceutical and personal care products. It disrupts the cell membranes of microorganisms, leading to their destruction.

Uses

Used in Pharmaceutical Industry:
1-(3 4-Dichlorophenyl)biguanide hydrochloride is used as an antiseptic and disinfectant for its ability to destroy microorganisms by disrupting their cell membranes.
Used in Personal Care Industry:
1-(3 4-Dichlorophenyl)biguanide hydrochloride is used as an ingredient in skincare products to maintain hygiene and prevent microbial growth.
Used in Wound Care:
1-(3 4-Dichlorophenyl)biguanide hydrochloride is used in wound care treatments to prevent infection and promote healing by eliminating harmful microorganisms.
Used in Water Purification:
1-(3 4-Dichlorophenyl)biguanide hydrochloride is used in the purification of water to ensure cleanliness and prevent the spread of waterborne diseases.
Used in Medical Treatments:
1-(3 4-Dichlorophenyl)biguanide hydrochloride has been studied for its potential use in treating certain medical conditions such as acne and fungal infections, due to its antimicrobial properties.

InChI:InChI=1/C8H9Cl2N5.ClH/c9-5-2-1-4(3-6(5)10)14-8(13)15-7(11)12;/h1-3H,(H6,11,12,13,14,15);1H

Upstream product

• 127099-85-8 dicyandiamide 
• 95-76-1 m,p-dichloroaniline 

Downstream Products

• 86177-50-6 4-(5-{2-[N'-(3,4-Dichloro-phenyl)-guanidino]-6-trifluoromethyl-pyrimidin-4-ylamino}-2-hydroxy-benzyl)-piperazine-1-carboxylic acid ethyl ester 
• 86177-54-0 N-[4-(4-Benzyloxy-3-diethylaminomethyl-phenylamino)-6-trifluoromethyl-pyrimidin-2-yl]-N'-(3,4-dichloro-phenyl)-guanidine 
• 86196-51-2 N-(4-{3-[(Cyclohexylmethyl-amino)-methyl]-4-hydroxy-phenylamino}-6-trifluoromethyl-pyrimidin-2-yl)-N'-(3,4-dichloro-phenyl)-guanidine 
• 86177-49-3 N-(3,4-Dichloro-phenyl)-N'-{4-[4-hydroxy-3-(4-methyl-piperazin-1-ylmethyl)-phenylamino]-6-trifluoromethyl-pyrimidin-2-yl}-guanidine 
• 86177-53-9 N-(3,4-Dichloro-phenyl)-N'-[4-(3-diethylaminomethyl-4-isopropoxy-phenylamino)-6-trifluoromethyl-pyrimidin-2-yl]-guanidine 
• 86177-52-8 N-(3,4-Dichloro-phenyl)-N'-[4-(3-diethylaminomethyl-4-ethoxy-phenylamino)-6-trifluoromethyl-pyrimidin-2-yl]-guanidine 
• 86177-48-2 N-(3,4-Dichloro-phenyl)-N'-[4-(4-hydroxy-3-pyrrolidin-1-ylmethyl-phenylamino)-6-trifluoromethyl-pyrimidin-2-yl]-guanidine 
• 86177-45-9 N-(3,4-Dichloro-phenyl)-N'-{4-[4-hydroxy-3-(isobutylamino-methyl)-phenylamino]-6-trifluoromethyl-pyrimidin-2-yl}-guanidine 
• 86177-51-7 N-(3,4-Dichloro-phenyl)-N'-[4-(3-dimethylaminomethyl-4-methoxy-phenylamino)-6-trifluoromethyl-pyrimidin-2-yl]-guanidine 
• 86177-47-1 N-(3,4-Dichloro-phenyl)-N'-(4-{3-[(ethyl-methyl-amino)-methyl]-4-hydroxy-phenylamino}-6-trifluoromethyl-pyrimidin-2-yl)-guanidine 
• 86177-44-8 N-(3,4-Dichloro-phenyl)-N'-[4-(3-ethylaminomethyl-4-hydroxy-phenylamino)-6-trifluoromethyl-pyrimidin-2-yl]-guanidine 
• 86177-46-0 N-(3,4-Dichloro-phenyl)-N'-[4-(3-dimethylaminomethyl-4-hydroxy-phenylamino)-6-trifluoromethyl-pyrimidin-2-yl]-guanidine 
• 86177-43-7 N-(3,4-Dichloro-phenyl)-N'-[4-(3-diethylaminomethyl-phenylamino)-6-trifluoromethyl-pyrimidin-2-yl]-guanidine 
• 86177-01-7 N-(3,4-Dichloro-phenyl)-N'-(4-hydroxy-6-trifluoromethyl-pyrimidin-2-yl)-guanidine 

Relevant articles and documents

BIGUANIDE COMPOUNDS AND USE THEREOF

The present invention relates to a biguanide compound and uses thereof. More specifically, the present invention relates to: a biguanide derivative exhibiting excellent effects in inhibiting cancer cell proliferation, cancer metastasis, and cancer recurrence; a manufacturing method of the biguanide derivative; and a pharmaceutical composition containing the biguanide derivative as an active component.

BIGUANIDE COMPOUNDS AND USE THEREOF

The present invention relates to biguanide compounds and use thereof, more particularly, to biguanide derivatives exhibiting excellent effects for inhibition of cancer cell proliferation and inhibition of cancer metastasis and recurrence, a method for pre