216978-21-1

Basic information

• Product Name: 1-(6-Chloro-1-oxohex-2-ynyl)-5-(1-hydroxyprop-2-enyl)-2,6,6-trimethylcyclohex-1-ene
• Synonyms: 1-(6-Chloro-1-oxohex-2-ynyl)-5-(1-hydroxyprop-2-enyl)-2,6,6-trimethylcyclohex-1-ene
• CAS NO: 216978-21-1
• Molecular Weight: 308.848
• Mol File: 216978-21-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(6-Chloro-1-oxohex-2-ynyl)-5-(1-hydroxyprop-2-enyl)-2,6,6-trimethylcyclohex-1-ene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(6-Chloro-1-oxohex-2-ynyl)-5-(1-hydroxyprop-2-enyl)-2,6,6-trimethylcyclohex-1-ene(216978-21-1)
• EPA Substance Registry System: 1-(6-Chloro-1-oxohex-2-ynyl)-5-(1-hydroxyprop-2-enyl)-2,6,6-trimethylcyclohex-1-ene(216978-21-1)

Safety Data

• Hazardous Substances Data: 216978-21-1(Hazardous Substances Data)

Upstream product

• 14267-92-6 1-chloro-4-pentyne 
• 216978-13-1 1-Acetoxymethyl-5-(1,3-dioxolan-2-yl)-2,6,6-trimethylcyclohex-1-ene 
• 216978-60-8 5-(1,3-Dioxolan-2-yl)-1-hydroxymethyl-2,6,6-trimethylcyclohex-1-ene 
• 216978-20-0 1-(6-Chloro-1-oxohex-2-ynyl)-5-(1,3-dioxolan-2-yl)-2,6,6-trimethylcyclohex-1-ene 
• 189444-00-6 1-(6-Chloro-1-hydroxyhex-2-ynyl)-5-(1,3-dioxolan-2-yl)-2,6,6-trimethylcyclohex-1-ene 
• 189443-99-0 1-Formyl-5-(1,3-dioxolan-2-yl)-2,6,6-trimethylcyclohex-1-ene 
• 144066-82-0 Acetic acid 2-isopropenyl-3-methyl-but-2-enyl ester 
• 144067-40-3 Acetic acid 5-formyl-2,6,6-trimethyl-cyclohex-1-enylmethyl ester 
• 52385-60-1 (3-methyl-2-methylethenyl)-2-buten-1-ol 
• 99978-27-5 2-(α-hydroxy-isopropyl)-3-methyl-crotonic acid ethyl ester 
• 100144-50-1 2-isopropenyl-3-methyl-crotonic acid methyl ester 
• 4412-05-9 2-isopropenyl-3-methyl-crotonic acid 
• 35044-52-1 ethyl 2-acetyl-3-methylbut-2-enoate 
• 3536-96-7 vinylmagnesium chloride 

Downstream Products

• 189443-91-2 1-(6-Iodo-1-oxohex-2-ynyl)-5-(1-oxoprop-2-enyl)-2,6,6-trimethylcyclohex-1-ene 
• 189444-02-8 1-(6-Chloro-1-oxohex-2-ynyl)-5-(1-oxoprop-2-enyl)-2,6,6-trimethylcyclohex-1-ene 

Relevant articles and documents

A tandem radical macrocyclisation-transannular cyclisation approach towards the taxanes

Separate treatment of the iodotrienedione 19 and the iododienynedione 38 with Bu3SnH-AIBN produces the corresponding taxane ring systems 25 (25-30%) and 56 (50-60%) respectively by way of tandem radical macrocyclisation-radical transannular cyc