210539-04-1

Basic information

• Product Name: 6-BENZYL-2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE
• Synonyms: 6-BENZYL-2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE;2-Chloro-5,6,7,8-tetrahydro-6-(phenylmethyl)-1,6-naphthyridine;6-benzyl-2-chloro-5,6,7,8-tetrahydro-1,6-naphthyridine hydrochloride
• CAS NO: 210539-04-1
• Molecular Formula: C₁₅H₁₅ClN₂
• Molecular Weight: 258.75
• Mol File: 210539-04-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 373.06 °C at 760 mmHg
• Flash Point: 179.421 °C
• Appearance: /
• Density: 1.227
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.621
• Storage Temp.: 2-8°C
• PKA: 5.70±0.20(Predicted)
• CAS DataBase Reference: 6-BENZYL-2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-BENZYL-2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE(210539-04-1)
• EPA Substance Registry System: 6-BENZYL-2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE(210539-04-1)

Safety Data

• Hazardous Substances Data: 210539-04-1(Hazardous Substances Data)

Usage

General Description

6-Benzyl-2-chloro-5,6,7,8-tetrahydro-1,6-naphthyridine is a chemical compound that belongs to the class of organic compounds known as 1,6-naphthyridines. It is also classified under the group of tetrahydro-1,6-naphthyridines, which consists of compounds that contain a tetrahydro-1,6-naphthyridine moiety, a structure made of a naphthyridine ring system, which is in turn made of two benzene rings joined together by two nonadjacent carbon atoms. This specific compound is characterized by the presence of a benzyl group and a chlorine atom attached to the naphthyridine core. Information on specific uses, toxicity, or reactivity of this compound is not readily available, suggesting it might be primarily used in scientific research or chemical industries.

InChI:InChI=1/C15H15ClN2/c16-15-7-6-13-11-18(9-8-14(13)17-15)10-12-4-2-1-3-5-12/h1-7H,8-11H2

Upstream product

• 210539-03-0 6-benzyl-3,4,5,6,7,8-hexahydro-1,6-naphthyridin-2(1H)-one 
• 23616-29-7 1,6-naphthyridin-2(1H)-one 
• 100-39-0 benzyl bromide 
• 16675-58-4 1-Benzyl-4-(1-pyrrolidinyl)-1,2,3,6-tetrahydro-pyridine 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 935838-05-4 N-(1-benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-acetamide 
• 601514-58-3 6-benzyl-5,6,7,8-tetrahydro-[1,6]-naphthyridin-2(1H)-one 

Downstream Products

• 676994-60-8 6-benzyl-2-methoxy-5,6,7,8-tetrahydro-[1,6]naphthyridine 
• 601514-81-2 4-(6-benzyl-7,8-dihydro-5H-1,6-naphthyridin-2-yl)morpholine 
• 1151665-05-2 6-benzyl-2-pyrrolidin-1-yl-5,6,7,8-tetrahydro-1,6-naphthyridine 
• 1151665-28-9 6-benzyl-2-chloro-8-methyl-5,6,7,8-tetrahydro-1,6-naphthyridine 
• 1151665-06-3 6-benzyl-N,N-dimethyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-amine 
• 1151665-24-5 6-benzyl-2-(1-ethylpropyl)-5,6,7,8-tetrahydro-1,6-naphthyridine 
• 1151665-15-4 2-chloro-7,8-dihydro-5H-[1,6]naphthyridine-6-carboxylic acid tert-butyl ester 
• 1151665-26-7 6-benzyl-2-tert-butoxy-5,6,7,8-tetrahydro-1,6-naphthyridine 
• 1151665-14-3 6-benzyl-2-isopropyl-5,6,7,8-tetrahydro-1,6-naphthyridine 
• 1151665-07-4 6-benzyl-N-isopropyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-amine 
• 1151665-25-6 6-benzyl-2-cyclopropyl-5,6,7,8-tetrahydro-1,6-naphthyridine 
• 1151665-18-7 6-benzyl-2-(1-cyclopropylethoxy)-5,6,7,8-tetrahydro-1,6-naphthyridine 
• 1151665-03-0 6-benzyl-2-[(3R)-3-methylmorpholin-4-yl]-5,6,7,8-tetrahydro-1,6-naphthyridine 
• 1151665-04-1 6-benzyl-2-[(3S)-3-methylmorpholin-4-yl]-5,6,7,8-tetrahydro-1,6-naphthyridine 

Relevant articles and documents

Compounds and methods of use

Compounds are provided according to Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein X1, X2, X3, X4, Y, A, L1, L2, R1, R2, R5, m and n are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of conditions.

ANTI-PULMONARY TUBERCULOSIS NITROIMIDAZOLE DERIVATIVE

Disclosed is a substituted nitroimidazole derivative, which is mainly used for treating related diseases caused by mycobacterial infections, such as Mycobacterium tuberculosis, especially being suitable for diseases caused by resistant Mycobacterium tuberculosis.

CONDENSED PYRIDINE DERIVATIVE AND USE THEREOF

Provided are a condensed pyridine derivative having a serotonin 5-HT2C receptor activation action, a prophylactic or therapeutic agent for a lower urinary tract symptom, obesity and/or organ prolapse and the like containing the condensed pyridine derivative, a screening method for a substance that increases leak point pressure upon a rise in the intravesical pressure or a prophylactic or therapeutic drug for stress urinary incontinence, a prophylactic or therapeutic drug for cystoceles or enteroceles, containing a substance that activates serotonin 5-HT2C receptor, and a method of screening for a therapeutic drug for cystoceles or enteroceles, including increasing an intravesical pressure after bilateral transection of the hypogastric nerve and pudendal nerve of an animal, and measuring a closure response in the urethra, the rectum or the vagina observed at that time. A serotonin 5-HT2C receptor activator containing a compound represented by the formula: wherein each symbol is as defined in the specification, or a salt thereof.