21021-99-8 Usage
Description
o-Oxanisidide, also known as ortho-oxanisidide, is an organic compound with the chemical formula C8H8O4. It is a derivative of oxanisidine, which is a type of heterocyclic compound. o-Oxanisidide is characterized by its unique molecular structure, which includes a central oxane ring fused with an isochromene ring. This structure endows o-Oxanisidide with various chemical and physical properties that make it suitable for a range of applications across different industries.
Uses
Used in Pharmaceutical Industry:
o-Oxanisidide is used as a potential tuberculostatic agent for the development of new drugs to treat tuberculosis. Its unique molecular structure allows it to target and inhibit the growth of Mycobacterium tuberculosis, the bacterium responsible for causing tuberculosis. The use of o-Oxanisidide in this application is based on its ability to interfere with the bacterial cell wall synthesis and other essential metabolic pathways, thereby exhibiting antimicrobial and anti-tuberculosis properties.
Used in Chemical Synthesis:
o-Oxanisidide is used as a key intermediate in the synthesis of various organic compounds, including dyes, pigments, and pharmaceuticals. Its versatile chemical structure allows for a range of chemical reactions, such as substitution, addition, and condensation, which can be exploited to produce a wide array of derivatives with diverse applications.
Used in Material Science:
o-Oxanisidide is used as a building block for the development of novel materials with specific properties, such as optical, electronic, and magnetic characteristics. Its unique molecular structure can be incorporated into the design of advanced materials, such as organic semiconductors, conductive polymers, and molecular magnets, which can find applications in various fields, including electronics, sensors, and energy storage devices.
Used in Research and Development:
o-Oxanisidide is used as a research tool in the study of various chemical and biological processes, as well as in the development of new synthetic methods and strategies. Its unique properties and reactivity make it an attractive candidate for exploring new reaction mechanisms, designing novel catalysts, and developing innovative synthetic routes to complex organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 21021-99-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,0,2 and 1 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 21021-99:
(7*2)+(6*1)+(5*0)+(4*2)+(3*1)+(2*9)+(1*9)=58
58 % 10 = 8
So 21021-99-8 is a valid CAS Registry Number.
21021-99-8Relevant articles and documents
CuI/Oxalic Diamide Catalyzed Coupling Reaction of (Hetero)Aryl Chlorides and Amines
Zhou, Wei,Fan, Mengyang,Yin, Junli,Jiang, Yongwen,Ma, Dawei
supporting information, p. 11942 - 11945 (2015/10/06)
A class of oxalic diamides are found to be effective ligands for promoting CuI-catalyzed aryl amination with less reactive (hetero)aryl chlorides. The reaction proceeds at 120 °C with K3PO4 as the base in DMSO to afford a wide range of (hetero)aryl amines in good to excellent yields. The bis(N-aryl) substituted oxalamides are superior ligands to N-aryl-N′-alkyl substituted or bis(N-alkyl) substituted oxalamides. Both the electronic nature and the steric property of the aromatic rings in ligands are important for their efficiency.
1H, 13C, 15N, 2D and Variable Temperature NMR Study of the Role of Hydrogen Bonding in the Structure and Conformation of Oxamide Derivatives
Martinez-Martinez, Francisco Javier,Ariza-Castolo, Armando,Tlahuext, Hugo,Tlahuextl, Margarita,Contreras, Rosalinda
, p. 1481 - 1485 (2007/10/02)
The structure and conformation of N,N'-bisoxamide (1); N,N'-bisoxamide (2); N,N'-bis(phenyl)oxamide (3); N,N'-bisoxamide (4); N,N'-bisoxamide (5); N-methylamide (6); N-methylamide (7); N-phenylmethylamide (8); N-methylamide (9) and N-methylamide (10) were unambiguously established by 1H, 13C, 15N, 2D and variable temperature NMR spectroscopy.A careful NMR investigation of the conformational behaviour in these systems was relevant.It has been found that the dicarbonylic group in compounds 1-5 has a trans geometry, stabilized by intramolecular hydrogen bonding and that they possess a C2 axis.Compounds 1 and 2 are planar and compounds 1, 2, 4 and 5 present the amidic proton coordinated by two oxygen atoms.
