20767-31-1

Basic information

• Product Name: BENZYLTRIPHENYLPHOSPHONIUM BROMIDE
• Synonyms: BENZYL TRIPHENYL PHOSPHOROUS BROMIDE;TZP
• CAS NO: 20767-31-1
• Molecular Formula: C₂₅H₂₂BrP
• Molecular Weight: 433.32
• EINECS: 215-908-4
• Mol File: 20767-31-1.mol
• Article Data: 2

Chemical Properties

• Melting Point: 295-298 °C(lit.)
• Appearance: /
• CAS DataBase Reference: BENZYLTRIPHENYLPHOSPHONIUM BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYLTRIPHENYLPHOSPHONIUM BROMIDE(20767-31-1)
• EPA Substance Registry System: BENZYLTRIPHENYLPHOSPHONIUM BROMIDE(20767-31-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: UN 1390 4.3/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 20767-31-1(Hazardous Substances Data)

Usage

Uses

Used in Chemical Research:
BENZYLTRIPHENYLPHOSPHONIUM BROMIDE is used as a phase transfer catalyst for facilitating the migration of compounds between different phases, which is crucial in various chemical reactions.
Used in Pharmaceutical Industry:
BENZYLTRIPHENYLPHOSPHONIUM BROMIDE is used as a catalyst in the synthesis of certain pharmaceutical compounds, aiding in the efficient production of drugs.
Used in Material Science:
In the field of material science, BENZYLTRIPHENYLPHOSPHONIUM BROMIDE is used as a catalyst to enhance the synthesis of specific materials, contributing to the development of new and improved materials with desired properties.
Used in Environmental Applications:
BENZYLTRIPHENYLPHOSPHONIUM BROMIDE is employed in environmental applications, such as the treatment of wastewater, where it acts as a catalyst to facilitate the degradation of pollutants and improve water quality.

InChI:InChI=1/C25H22P.BrH/c1-5-13-22(14-6-1)21-26(23-15-7-2-8-16-23,24-17-9-3-10-18-24)25-19-11-4-12-20-25;/h1-20H,21H2;1H/q+1;/p-1

Upstream product

• 100-39-0 benzyl bromide 
• 603-35-0 triphenylphosphine 

Downstream Products

• 73249-30-6 3-((E)-1-Methyl-2-phenyl-vinyl)-pyridine 
• 1694-20-8 trans-4-nitrostilbene 
• 6624-53-9 (Z)-1-nitro-4-(2-phenylethenyl)-benzene 
• 71265-08-2 dimethyl (E)-1,2-diphenylethenylphosphonate 
• 71265-09-3 dimethyl (Z)-1,2-diphenylethenylphosphonate 
• 1381940-20-0 (E)-5-styryl-1H-indole 
• 16721-45-2 triphenyl(phenylmethylene)phosphorane 
• 364078-08-0 4-benzylidene-N-tert-Boc-L-proline 
• 107902-38-5 Dimethyl-[2-((E)-styryl)-pyrrol-1-yl]-amine 
• 107902-39-6 1-Benzenesulfonyl-2-((E)-styryl)-1H-pyrrole 
• 123200-70-4 (Z)-1,3,5-triphenylpent-1-ene 
• 123200-69-1 (E)-pent-1-ene-1,3,5-triyltribenzene 
• 2433-77-4 (Z)-1-(1-methyl-2-pyrrolyl)-2-phenylethene 
• 2761-79-7 (E)-1-Methyl-2-(2-phenylethenyl)-1H-pyrrole 

Relevant articles and documents

ARYL-SULFONAMIDE AND ARYL-SULFONE DERIVATIVES AS TRPML MODULATORS

The new arylsulfonamide and arylsulfone derivatives are modulators of TRPML and are useful in treating disorders related to TRPML activities and lysosome functions such as acid-related disorders and cancer.

(E)-5-styryl-1H-indole and (E)-6-styrylquinoline derivatives serve as probes for β-amyloid plaques

We report the synthesis and biological evaluation of novel (E)-5-styryl-1H-indole and (E)-6-styrylquinoline derivatives as probes for imaging β-amyloid (Aβ) plaques. These derivatives showed binding affinities for Aβ1-40 aggregates with Ki values varying from 4.1 to 288.4 nM. (E)-5-(4-iodostyryl)-1H-indole (8) clearly stained Aβ plaques in the brain sections of Alzheimer's disease (AD) model mice (APP/PS1). Furthermore, autoradiography for [125I]8 displayed intense and specific labeling of Aβ plaques in the brain sections mentioned above with low background. In biodistribution experiments using normal mice [ 125I]8 showed high initial brain uptake followed by rapid washout (4.27 and 0.64% ID/g at 2 and 30 min post injection, respectively). These findings suggests that [123I]8 may be a potential SPECT imaging agent for detecting Aβ plaques in AD brain.