204764-72-7

Basic information

• Product Name: C₅₇H₇₉NO₁₅Si
• Synonyms: C₅₇H₇₉NO₁₅Si
• CAS NO: 204764-72-7
• Molecular Weight: 1046.34
• Mol File: 204764-72-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₅₇H₇₉NO₁₅Si(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₇H₇₉NO₁₅Si(204764-72-7)
• EPA Substance Registry System: C₅₇H₇₉NO₁₅Si(204764-72-7)

Safety Data

• Hazardous Substances Data: 204764-72-7(Hazardous Substances Data)

Upstream product

• 143615-03-6 (4S,5R)-3-(tert-butoxycarbonyl)-2,2-dimethyl-4-phenyloxazolidine-5-carboxylic acid 
• 204764-71-6 C₄₀H₅₈O₁₁Si 
• 151672-48-9 10-deacetyl-10-(S-methylxanthyl)-7-(triethylsilyl)baccatin III 
• 140-88-5 ethyl acrylate 

Relevant articles and documents

Synthesis and cytotoxic activity of novel 10-alkylated docetaxel analogs

An alkylation method of docetaxel at the C-10 position has been established by a radical coupling reaction using a 10-xanthate derivative of 7-O-TES-10-deacetylbaccatin III and appropriate alkenes. In addition the cytotoxic activity of 10-alkylated docetaxel analogs was evaluated. Among these analogs, a derivative having a methoxycarbonyl group at the end of the alkyl moiety exhibited more potent cytotoxic activity than docetaxel.