2040-15-5

Basic information

• Product Name: 2,4,6-TRIMETHYL PROPIOPHENONE
• Synonyms: 2,4,6-TRIMETHYL PROPIOPHENONE;PROPIOMESITYLENE;2,4,6-TRIMETHYL PROPIOPHENONE 97%;1-Mesitylpropan-1-one;1-Mesityl-1-propanone
• CAS NO: 2040-15-5
• Molecular Formula: C₁₂H₁₆O
• Molecular Weight: 176.25
• Product Categories: Aromatic Propiophenones (substituted)
• Mol File: 2040-15-5.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,4,6-TRIMETHYL PROPIOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-TRIMETHYL PROPIOPHENONE(2040-15-5)
• EPA Substance Registry System: 2,4,6-TRIMETHYL PROPIOPHENONE(2040-15-5)

Safety Data

• Hazardous Substances Data: 2040-15-5(Hazardous Substances Data)

Usage

General Description

2,4,6-Trimethyl propiophenone is a chemical compound with the molecular formula C12H14O. It is a colorless to pale yellow liquid with a strong odor, and it is used primarily as a fragrance and flavor ingredient in the cosmetic and food industries. It is also used as an intermediate in the production of pharmaceuticals and other organic compounds. Additionally, it has potential applications in the field of organic synthesis and as a solvent in chemical reactions. While 2,4,6-Trimethyl propiophenone is generally regarded as safe for use in these applications, proper handling and storage procedures should be followed to minimize the risk of exposure and adverse health effects.

Upstream product

• 79-03-8 propionyl chloride 
• 108-67-8 1,3,5-trimethyl-benzene 
• 123-62-6 propionic acid anhydride 
• 40916-25-4 α-mesityl-α-ethylmethanol 
• 1051488-22-2 1-(2,4,6-trimethylphenyl)prop-2-en-1-ol 
• 938-18-1 mesitylene-2-carboxylic acid chloride 
• 854652-39-4 1-mesityl-2-methyl-3-phenyl-propane-1,3-dione 
• 117873-84-4 β-Ethyl-α,β-dimesitylethenol 
• 4225-93-8 2-bromo-2',4',6'-trimethylpropiophenone 
• 7732-18-5 water 
• 67-64-1 acetone 
• 858491-19-7 2,4,6-trimethyl-benzoic acid p-tolyl ester 
• 925-90-6 ethylmagnesium bromide 
• 4456-78-4 1-mesityl-2-propenone 

Downstream Products

• 63815-32-7 3-mesityl-2-methyl-3-oxo-propionic acid 
• 72656-50-9 3-hydroxy-1-mesityl-2-methyl-3-phenyl-propan-1-one 
• 4810-04-2 1,3,5-trimethyl-2-propyl-benzene 
• 40916-25-4 α-mesityl-α-ethylmethanol 
• 55610-37-2 2,4,6-trimethyl-3,5-dinitro-benzoic acid 
• 854652-87-2 1-mesityl-propane-1,2-dione 
• 854652-39-4 1-mesityl-2-methyl-3-phenyl-propane-1,3-dione 
• 105340-75-8 Propionylnitromesitylen 
• 3453-83-6 mesitylene sulfonic acid 
• 4225-93-8 2-bromo-2',4',6'-trimethylpropiophenone 
• 72657-91-1 Lithium; (E)-1-(2,4,6-trimethyl-phenyl)-propen-1-olate 
• 117775-76-5 (E)Ethyl mesityl ketone potassium enolate 
• 117775-76-5 (Z)Ethyl mesityl ketone potassium enolate 
• 61878-66-8 3-Hydroxy-2-methyl-3-phenyl-1-(2,4,6-trimethyl-phenyl)-propan-1-one 

Relevant articles and documents

Synthetic utility of iodic acid in the oxidation of benzylic alcohols to aromatic aldehydes and ketones

Various primary and secondary benzylic alcohols were efficiently oxidized to aromatic aldehydes and aromatic ketones with iodic acid in DMF at 60?°C for 2?h and with iodic acid in the presence of TEMPO (5?mol?%) in DMF at room temperature, respectively. The former method was effective for the oxidation of sterically hindered alcohols at 60?°C and the latter method was effective for the oxidation of less sterically hindered alcohols at room temperature.

Pentamethylcyclopentadienyl ruthenium: an efficient catalyst for the redox isomerization of functionalized allylic alcohols into carbonyl compounds

The catalytic activity of the ruthenium(II) complex [RuCp*(CH3CN)3][PF6] 1 in the transposition of allylic alcohols into carbonyl compounds, in acetonitrile, is reported. This catalyst has proven to be able to catalyze the transformation of poorly reactive and/or functionalized substrates under smooth conditions.

A Novel Friedel-Crafts Reaction of Hindered Ketones

Mesitylene has been shown to react with acetyl chloride in the presence of aluminium chloride to form 1,1-dimesitylethene.Acetomesitylene has been demonstrated to be an intermediate in the reaction, which proceeds in the second step by nucleophilic attack by the arene on the carbonyl group of acetomesitylene, which is activated by the formation of a polarized complex with aluminum chloride.Mesitylene reacts similarly with propionyl chloride, forming 1,1-dimesitylpropene; propiomesitylene is an intermediate.Steric and electronic factors responsible for this unique Friedel-Crafts reaction are discussed.