2039-83-0

Basic information

• Product Name: 3,4-DICHLOROSTYRENE
• Synonyms: 1,2-Dichloro-4-vinylbenzene;Benzene, 1,2-dichloro-4-ethenyl-;benzene,1,2-dichloro-4-ethenyl-;styrene,3,4-dichloro-;3,4-DICHLOROSTYRENE;3,4-Dichlorostyrene, stabilized, 95%;3,4-Dichlorostyrol;3,4-Dichlorostyrolene
• CAS NO: 2039-83-0
• Molecular Formula: C₈H₆Cl₂
• Molecular Weight: 173.04
• EINECS: 218-023-1
• Product Categories: Styrenes;monomer
• Mol File: 2039-83-0.mol
• Article Data: 9

Chemical Properties

• Melting Point: 48.5°C (estimate)
• Boiling Point: 230.44°C (rough estimate)
• Flash Point: 101.7 °C
• Appearance: Clear colorless to yellow liquid
• Density: 1.2560
• Vapor Pressure: 0.0638mmHg at 25°C
• Refractive Index: 1.5857 (estimate)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3,4-DICHLOROSTYRENE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DICHLOROSTYRENE(2039-83-0)
• EPA Substance Registry System: 3,4-DICHLOROSTYRENE(2039-83-0)

Safety Data

• Hazardous Substances Data: 2039-83-0(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless to yellow liquid

InChI:InChI=1/C8H6Cl2/c1-2-6-3-4-7(9)8(10)5-6/h2-5H,1H2

Upstream product

• 1779-49-3 Methyltriphenylphosphonium bromide 
• 6287-38-3 3,4-dichlorobenzaldehyde 
• 3112-85-4 methylphenylsulfonate 
• 1805-32-9 3,4-dichlorobenzyl alcohol 
• 53547-61-8 vinyl trifluoromethanesulfonate 
• 151169-75-4 3,4-dichlophenylboronic acid 
• 136272-28-1 1-(3,4-dichlorophenyl)-2-(trimethylsilyl)ethanol 
• 2642-63-9 3',4'-dichloroacetophenone 
• 1475-11-2 1-(3,4-dichlorophenyl)ethan-1-ol 
• 74-85-1 ethene 
• 3024-72-4 3,4-dichlorobenzoyl chloride 
• 136272-23-6 Trifluoro-acetic acid 1-(3,4-dichloro-phenyl)-2-trimethylsilanyl-ethyl ester 
• 65426-63-3 1-acetoxy-1-(3,4-dichloro-phenyl)-ethane 
• 491-35-0 C₆H₄NCH₂CHCCH₂ 

Downstream Products

• 51-44-5 3,4-dichlorbenzoic acid 
• 42981-08-8 2,3',4'-trichloroacetophenone 
• 91309-68-1 1,2-Dichloro-4-((Z)-2-chloro-vinyl)-benzene 
• 91309-69-2 1,2-Dichloro-4-((E)-2-chloro-vinyl)-benzene 
• 113337-38-5 1-(3,4-dichlorophenyl)-2-hydroxyethan-1-one 
• 6287-38-3 3,4-dichlorobenzaldehyde 
• 1430232-30-6 2-((3R,8S)-3-(3,4-dichlorophenyl)-2,3,7,8-tetrahydrobenzofuro[5,6-b][1,4]dioxin-8-yl)acetic acid 
• 1430232-31-7 2-((3S,8S)-3-(3,4-dichlorophenyl)-2,3,7,8-tetrahydrobenzofuro[5,6-b][1,4]dioxin-8-yl)acetic acid 

Relevant articles and documents

Reaction progress analysis: Powerful tool for understanding suzuki-miyaura reaction and control of polychlorobiphenyl impurity

Cross coupling of unsaturated aryl or vinyl triflates/halides with aryl boronic acids using Pd as catalyst (Suzuki coupling) have become increasingly attractive for making the heterocoupled product (Ar-Ar′). However, most Pd cycle reactions produce some h

Regioselective Three-Component Synthesis of Vicinal Diamines via 1,2-Diamination of Styrenes

The vicinal diamine motif plays a significant role in natural products, drug design, and organic synthesis, and development of synthetic methods for the synthesis of diamines is a long-standing interest. Herein, we report a regioselective intermolecular three-component vicinal diamination of styrenes with acetonitrile and azodicarboxylates. The diamination products can be produced in moderate to excellent yields via the Ritter reaction. Synthetic applications and theoretical studies of this reaction have been conducted.

Benzocarbazoles dioxane derivatives, its preparation process and its use in medicine

The invention relates to a benzodioxane derivative, a preparation method thereof and application of the derivative in medicines. Specifically, the invention relates to a novel benzodioxane derivative shown as a formula (I), medial salt thereof or a medicine composition containing the derivative, and a preparation method of the derivative. The invention further relates to a use of the benzodioxane derivative and the medial salt thereof or the medicine composition containing the derivative in preparing therapeutic agent, especially GPR 40 agonist, and a drug for treating the diseases such as diabetes, metabolic disorders and the like, wherein each substituent group in the formula (I) is as defined in the description.

NOVEL INHIBITORS

The invention relates to novel pyrrolidine derivatives of formula (I): wherein R1, R2 and R3 are as defined herein, as inhibitors of glutaminyl cyclase (QC, EC 2.3.2.5). QC catalyzes the intramolecular cyclization of N-terminal glutamine residues into pyroglutamic acid (5-oxo-prolyl, pGlu*) under liberation of ammonia and the intramolecular cyclization of N-terminal glutamate residues into pyroglutamic acid under liberation of water.