20127-63-3

Basic information

• Product Name: 1-Formyl-β-carboline
• Synonyms: 1-Formyl-β-carboline;β-Carboline-1-carbaldehyde;NSC 149850;1-Formyl-beta-carboline;9H-Pyrido[3,4-b]indole-1-carboxaldehyde;beta-Carboline-1-carbaldehyde;Kumujian C;9H-Beta-carboline-1-carboxaldehyde
• CAS NO: 20127-63-3
• Molecular Formula: C₁₂H₈N₂O
• Molecular Weight: 196.20472
• Mol File: 20127-63-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 440.8°C at 760 mmHg
• Flash Point: 220.8°C
• Appearance: /
• Density: 1.392
• Vapor Pressure: 5.72E-08mmHg at 25°C
• Refractive Index: 1.818
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 1-Formyl-β-carboline(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Formyl-β-carboline(20127-63-3)
• EPA Substance Registry System: 1-Formyl-β-carboline(20127-63-3)

Safety Data

• Hazardous Substances Data: 20127-63-3(Hazardous Substances Data)

Usage

Description

1-Formyl-β-carboline is an alkaloid compound that can be isolated from the heartwood of Picrasma quassinoides. It possesses inhibitory properties against the growth of certain Staphylococcus aureus strains, making it a potential candidate for applications in various industries.

Uses

Used in Pharmaceutical Industry:
1-Formyl-β-carboline is used as an antimicrobial agent for its ability to inhibit the growth of specific Staphylococcus aureus strains. This property makes it a valuable component in the development of new antibiotics or treatments targeting drug-resistant bacterial infections.
Used in Research and Development:
1-Formyl-β-carboline can be utilized in research settings to study its potential applications and mechanisms of action against various pathogens. This may lead to the discovery of new therapeutic agents or a better understanding of the compound's properties and interactions with biological systems.

Synthesis Reference(s)

Tetrahedron, 50, p. 12329, 1994 DOI: 10.1016/S0040-4020(01)89542-9

InChI:InChI=1/C12H8N2O/c15-7-11-12-9(5-6-13-11)8-3-1-2-4-10(8)14-12/h1-7,14H

Upstream product

• 668987-20-0 methyl 1-acetyl-4-[(β-carbolin-1-yl)methyl]-5-vinyl-1,4-dihydropyridine-3-carboxylate 

Downstream Products

• 1613078-22-0 (E)-1-phenyl-3-(9H-pyrido[3,4-b]indol-1-yl)prop-2-en-1-one 
• 1613078-23-1 (E)-1-(4-methoxyphenyl)-3-(9H-pyrido[3,4-b]indol-1-yl)prop-2-en-1-one 
• 1613078-24-2 (E)-1-(3,4-dimethoxyphenyl)-3-(9H-pyrido[3,4-b]indol-1-yl)prop-2-en-1-one 
• 1613078-25-3 (E)-1-(3,4,5-trimethoxyphenyl)-3-(9H-pyrido[3,4-b]indol-1-yl)prop-2-en-1-one 
• 1613078-26-4 (E)-3-(9H-pyrido[3,4-b]indol-1-yl)-1-p-tolylprop-2-en-1-one 
• 1613078-27-5 (E)-1-(4-bromophenyl)-3-(9H-pyrido[3,4-b]indol-1-yl)prop-2-en-1-one 
• 1613078-28-6 (E)-1-(4-chlorophenyl)-3-(9H-pyrido[3,4-b]indol-1-yl)prop-2-en-1-one 
• 1613078-29-7 (E)-1-(4-fluorophenyl)-3-(9H-pyrido[3,4-b]indol-1-yl)prop-2-en-1-one 
• 203717-13-9 9-benzyl-9H-pyrido[3,4-b]indole-1-carbaldehyde 
• 20127-60-0 pavettine 
• 1379826-55-7 methyl 2-{hydroxy[9-(3,5-dimethoxybenzyl)-9H-β-carbolin-1-yl]methyl}acrylate 
• 1379826-54-6 C₂₄H₂₁N₃O₃ 
• 1379826-28-4 9-(3,5-dimethoxybenzyl)-9H-β-carboline-1-carbaldehyde 
• 479-43-6 canthin-6-one 

Relevant articles and documents

Total Synthesis of the Proposed Structures of Indole Alkaloids Lyaline and Lyadine

The harman-1,4-dihydropyridines 1 and 2, which constitute the originally proposed structures for the indole alkaloids lyaline and lyadine, have been synthesized, and their NMR data have been compared with those available for the natural products. Due to the discrepancies in the spectral data, the structures of lyadine and lyaline should be revised.