200417-33-0

Basic information

• Product Name: 1H-4,5-dihydro-3-methyl-5-(4-hydroxyphenyl)pyrazole
• Synonyms: 1H-4,5-dihydro-3-methyl-5-(4-hydroxyphenyl)pyrazole
• CAS NO: 200417-33-0
• Molecular Weight: 176.218
• Mol File: 200417-33-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-4,5-dihydro-3-methyl-5-(4-hydroxyphenyl)pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-4,5-dihydro-3-methyl-5-(4-hydroxyphenyl)pyrazole(200417-33-0)
• EPA Substance Registry System: 1H-4,5-dihydro-3-methyl-5-(4-hydroxyphenyl)pyrazole(200417-33-0)

Safety Data

• Hazardous Substances Data: 200417-33-0(Hazardous Substances Data)

Upstream product

• 22214-30-8 (E)-4-(4-hydroxyphenyl)-3-buten-2-one 

Downstream Products

• 313394-46-6 1-[5-(4-hydroxyphenyl)-3-methyl-4,5-dihydro-1H-pyrazol-1-yl]ethanone 

Relevant articles and documents

Synthesis, structure, and antibacterial activity of novel 5-arylpyrazole derivatives

A series of novel 1-(acetyl,carboxamide,carbothioamide)substituted-5- (substituted-phenyl)-3-methy-4,5-dihydropyrazole derivatives have been synthesized and characterized by 1H NMR, IR, ESI-MS, and elemental analysis. Compounds 6h and 6q were further characterized by single crystal X-ray structural analysis. All of the compounds have been screened for their antibacterial potential in vitro against Bacillus subtilis ATCC 6633, Escherichia coli ATCC 35218, Pseudomonas fluorescens ATCC 13525, and Staphylococcus aureus ATCC 6538. Among the tested compounds, some of them display significant activity against the tested strains, and compounds 5ac and 6h show potent activity with a minimum inhibitory concentration value of 1.562 ?g mL?1 against B. subtilis ATCC 6633, which is comparable to the positive control penicillin. Structure?effect relationships are also discussed based on the experimental data. CSIRO 2008.