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  • 189321-66-2 Structure
  • Basic information

    1. Product Name: 4-BOC-2-MORPHOLINECARBOXYLIC ACID
    2. Synonyms: BOC-COP;BOC-COP-OH;BOC-(R,S)-2-CARBOXYMORPHOLINE;4-BOC-2-MORPHOLINECARBOXYLIC ACID;4-(TERT-BUTOXYCARBONYL)MORPHOLINE-2-CARBOXYLIC ACID;RARECHEM EM WB 0087;(R,S)-BOC-2-CARBOXYMORPHOLINE;N-Boc-2-morpholinecarboxylic acid
    3. CAS NO:189321-66-2
    4. Molecular Formula: C10H17NO5
    5. Molecular Weight: 231.25
    6. EINECS: N/A
    7. Product Categories: pharmacetical;Heterocycles series;Carboxylic Acids;Morpholines & Thiomorpholines;Carboxylic Acids;Morpholines & Thiomorpholines
    8. Mol File: 189321-66-2.mol
    9. Article Data: 0
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 369.473 °C at 760 mmHg
    3. Flash Point: 177.251 °C
    4. Appearance: /
    5. Density: 1.23 g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.492
    8. Storage Temp.: Store at -15°C
    9. Solubility: DMSO (Slightly), Ethyl Acetate (Slightly, Heated)
    10. PKA: 3.25±0.20(Predicted)
    11. CAS DataBase Reference: 4-BOC-2-MORPHOLINECARBOXYLIC ACID(CAS DataBase Reference)
    12. NIST Chemistry Reference: 4-BOC-2-MORPHOLINECARBOXYLIC ACID(189321-66-2)
    13. EPA Substance Registry System: 4-BOC-2-MORPHOLINECARBOXYLIC ACID(189321-66-2)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36-51
    3. Safety Statements: 26
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 189321-66-2(Hazardous Substances Data)

189321-66-2 Usage

Description

4-BOC-2-MORPHOLINECARBOXYLIC ACID, also known as 4-(1,1-Dimethylethyl) Ester 2,4-Morpholinedicarboxylic Acid, is an organic compound with the chemical formula C10H17NO4. It is a white to off-white powder and is primarily used in the pharmaceutical industry for the synthesis of specific inhibitors.

Uses

Used in Pharmaceutical Industry:
4-BOC-2-MORPHOLINECARBOXYLIC ACID is used as a key intermediate in the synthesis of potent and selective 3-phosphoinositide-dependent kinase 1 (PDK1) inhibitors. These inhibitors play a crucial role in the treatment of multiple myelomas, a type of blood cancer. By targeting PDK1, these inhibitors can potentially disrupt the signaling pathways that contribute to the growth and survival of cancer cells, offering a promising therapeutic approach for patients with multiple myelomas.

Check Digit Verification of cas no

The CAS Registry Mumber 189321-66-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,9,3,2 and 1 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 189321-66:
(8*1)+(7*8)+(6*9)+(5*3)+(4*2)+(3*1)+(2*6)+(1*6)=162
162 % 10 = 2
So 189321-66-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H17NO5/c1-10(2,3)16-9(14)11-4-5-15-7(6-11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)

189321-66-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-[(2-methylpropan-2-yl)oxycarbonyl]morpholine-2-carboxylic acid

1.2 Other means of identification

Product number -
Other names (d1)-4-(tert-butoxycarbonyl)morpholin-2-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:189321-66-2 SDS

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