188057-49-0 Usage
Description
5-BROMO-2-IODOPYRIDIN-3-OL is an organic compound characterized by its unique molecular structure, featuring a pyridine ring with a bromine atom at the 5th position and an iodine atom at the 2nd position, along with a hydroxyl group at the 3rd position. 5-BROMO-2-IODOPYRIDIN-3-OL is known for its potential applications in various fields due to its distinct chemical properties.
Uses
Used in Pharmaceutical Industry:
5-BROMO-2-IODOPYRIDIN-3-OL is used as a key intermediate compound in the synthesis of bicyclic heterocyclic compounds. These synthesized compounds have been identified as potential inhibitors of acetyl-CoA carboxylase (ACC), an enzyme that plays a crucial role in cellular lipid metabolism. By inhibiting ACC, these bicyclic heterocyclic compounds can potentially be used in the development of treatments for various metabolic disorders and conditions related to lipid metabolism, such as obesity, type 2 diabetes, and cardiovascular diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 188057-49-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,8,0,5 and 7 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 188057-49:
(8*1)+(7*8)+(6*8)+(5*0)+(4*5)+(3*7)+(2*4)+(1*9)=170
170 % 10 = 0
So 188057-49-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H3BrINO/c6-3-1-4(9)5(7)8-2-3/h1-2,9H
188057-49-0Relevant articles and documents
INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS
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Page/Page column 492, (2021/09/11)
The present invention is directed to indazole and azaindazole compounds which are inhibitors of LRRK2 and are useful in the treatment of CNS disorders.
PYRIDINE COMPOUNDS AS ALLOSTERIC SHP2 INHIBITORS
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Paragraph 00429; 00460, (2018/08/12)
The present disclosure is directed to inhibitors of SHP2 and their use in the treatment of disease. Also disclosed are pharmaceutical compositions comprising the same.
FUROPYRIDINES AS INHIBITORS OF PROTEIN KINASES
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Page/Page column 67, (2015/11/23)
The invention relates to furo[3,2-b]pyridines substituted at least in position 5 as inhibitors of protein kinases, regulators or modulators, methods of preparation thereof, pharmaceutical compositions containing the compounds, and pharmaceutical use of the compounds and compositions in the treatment of the diseases such as, for example, cancer or neurodegenerative diseases. (Formula (I))
