180903-15-5Relevant articles and documents
One-pot synthesis of tetrasubstituted pyrazoles - Proof of regiochemistry
Hanefeld, Ulf,Rees, Charles W.,White, Andrew J. P.,Williams, David J.
, p. 1545 - 1552 (2007/10/03)
1-Alkyl-5-amino-3-aryl-4-cyanopyrazoles, useful intermediates for fused heterocyclic systems, are synthesised by a one-pot three-step procedure from acid chlorides, malononitrile and alkylhydrazines. The regiochemistry of the hydrazine incorporation was p