17537-64-3Relevant articles and documents
Convenient procedure for dethioketalisation in nitrogen heterocycles
Giri,Sankar
, p. 1795 - 1800 (1993)
Regeneration of carbonyl compounds from the corresponding thioketals in nitrogen heterocycles have been effected using Dowex 50W acidic catalyst in reasonable yields.
Overcoming Electron-Withdrawing and Product-Inhibition Effects by Organocatalytic Aerobic Oxidation of Alkylpyridines and Related Alkylheteroarenes to Ketones
Wang, Hua,Liu, Jie,Qu, Jian-Ping,Kang, Yan-Biao
, p. 3942 - 3948 (2020/03/23)
An organocatalyzed aerobic benzylic C-H oxidation of alkyl and aryl heterocycles has been developed. This transition metal-free method is able to overcome the electron-withdrawing effect as well as product-inhibition effects in heterobenzylic radical oxidation. A variety of ketones bearing N-heterocyclic groups could be prepared under relatively mild conditions with moderate to high yields.
Na 2 CO 3-Catalyzed N-Acylation of Indoles with Alkenyl Carboxylates
Zhou, Xiao-Yu,Chen, Xia
supporting information, p. 516 - 521 (2019/01/10)
The N-acylation of indoles has been accomplished via inorganic base catalysis. It provided an efficient and simple catalysis system for the preparation of N-acylindoles with alkenyl carboxylates as acylating agents. A broad variety of indoles undergo the smooth N-acylation using Na 2 CO 3 as catalyst in MeCN at 120? °C to give the corresponding N-acylindoles in good to excellent yields.
Based on carboxylic acid allyl ester as the acylation reagent N - acyl indoles preparation method (by machine translation)
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Paragraph 0041-0043, (2018/12/02)
Based on carboxylic acid allyl ester as the acylation reagent N - acyl indoles preparation method, which belongs to the medical and chemical intermediates and related chemical technical field. This method uses the indole compounds and carboxylic acid allyl ester as the raw material, in the catalysis of alkali, realizes the N - acyl indoles of green, efficient synthesis. The method has high selectivity, mild reaction conditions, functional group compatibility is good, wide substrate range, environment-friendly and the like. Because the N - acyl indoles is an important organic synthetic intermediates, in organic synthesis and in the field of pharmacy has very wide application, therefore, the invention has great application value and social and economic benefits. (by machine translation)