17514-68-0Relevant articles and documents
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Chapman,N.B. et al.
, p. 1404 - 1407 (1972)
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Preparation process of sertaconazole nitrate
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Paragraph 0025; 0028-0029, (2021/04/26)
The invention provides a preparation process of sertaconazole nitrate. The preparation process comprises the following steps: acylating, cyclizing, brominating, salifying and refining to obtain the finished product of sertaconazole nitrate. By adopting the preparation process of sertaconazole nitrate, the obtained finished product of sertaconazole nitrate is high in purity and high in yield. By adopting the preparation process of the sertaconazole nitrate, the raw materials are fully reacted, the generation of impurities is effectively reduced, the purity of a crude product is greatly improved, finally, the finished product of the sertaconazole nitrate obtained by adopting a refining process is high in purity and yield, and the production benefit of a sertaconazole nitrate bulk drug is effectively improved.
BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER
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Page/Page column 68, (2012/01/13)
A compound of formula (I). The compound is useful for treating cancer and inflammatory diseases. A pharmaceutical composition containing the compound.