17427-37-1 Usage
Description
1-(2-ISOTHIOCYANATO-ETHYL)-4-METHOXY-BENZENE, also known as Isothiocyanatoethylmethoxybenzene, is a chemical compound with the molecular formula C10H11NOS. It is an isothiocyanate, a functional group consisting of a sulfur atom, a carbon atom, and a nitrogen atom. 1-(2-ISOTHIOCYANATO-ETHYL)-4-METHOXY-BENZENE is known for its potential biological activities, including anticancer, antimicrobial, and antioxidant properties.
Uses
Used in Pharmaceutical Industry:
1-(2-ISOTHIOCYANATO-ETHYL)-4-METHOXY-BENZENE is used as a pharmaceutical agent for its potential anticancer properties. It may contribute to the development of new drugs targeting various types of cancer due to its biological activities.
Used in Agriculture:
In the agricultural industry, 1-(2-ISOTHIOCYANATO-ETHYL)-4-METHOXY-BENZENE is used as an insect repellant and in pest control formulations. Its potential role in these applications can help protect crops from harmful insects and pests, thereby increasing agricultural productivity.
Used in Biotechnology:
1-(2-ISOTHIOCYANATO-ETHYL)-4-METHOXY-BENZENE is utilized in biotechnology for its antimicrobial properties. It can be employed in the development of new antimicrobial agents to combat various microbial infections, contributing to advancements in healthcare and disease prevention.
Check Digit Verification of cas no
The CAS Registry Mumber 17427-37-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,4,2 and 7 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 17427-37:
(7*1)+(6*7)+(5*4)+(4*2)+(3*7)+(2*3)+(1*7)=111
111 % 10 = 1
So 17427-37-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H11NOS/c1-12-10-4-2-9(3-5-10)6-7-11-8-13/h2-5H,6-7H2,1H3
17427-37-1Relevant articles and documents
Synthesis and SAR of novel capsazepine analogs with significant anti-cancer effects in multiple cancer types
Chapa, Jorge De La,Valdez, Matthew,Ruiz, Franscisco,Gonzales, Keith,Mitchell, Wes,McHardy, Stanton F.,Hart, Matthew,Polusani, Srikanth R.,Gonzales, Cara B.
, p. 208 - 215 (2018/12/11)
We previously demonstrated that capsazepine (CPZ), a synthetic transient receptor potential Vanilloid subtype 1 (TRPV1) antagonist, has significant anti-cancer effects in vivo. The purpose of this study was to develop more potent analogs based upon CPZ pharmacophore and structure–activity relationships (SAR) across analogs. We generated 30 novel compounds and screened for their anti-proliferative effects in cultured HeLa cervical cancer cells. Cell viability assays identified multiple compounds with IC50s 50 50s of 1–2.5 μM in HSC-3and PC-3cells. Thus, we propose that these novel CPZ analogs may serve as efficacious therapeutic agents against multiple tumor types that warrant further development for clinical application.
Bronchorelaxing compounds
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Page/Page column 16, (2010/02/13)
A compound of the general formula (I) including its pharmaceutically acceptable acid addition salts wherein A is CHR9, wherein R9 is H, C1-C6 alkyl; n is 1-3; B is CHR10, wherein R10 is H, C1-C6 alkyl; m is 1 or 2; D is O or S or optionally NR16, wherein R16 is H, C1-C6 alkyl or C2-C6 acyl; E is CR11R12 or NR13, wherein R11 and R12 are, independent of each other, H or C1-C6 alkyl, R13 is H or C1-C6 alkyl; F is C1-C18 alkyl which may be mono- or di-unsaturated and/or substituted, is useful in treating and preventing pulmonary disease characterized by bronchoconstriction. Also disclosed are pharmaceutical compositions comprising the compound and methods for their manufacture.