17282-02-9

Basic information

• Product Name: 3-BROMO-2-HYDROXY-5-METHYLPYRIDINE
• Synonyms: 3-BROMO-5-METHYLPYRIDIN-2-OL;3-BROMO-5-METHYL-2(1H)-PYRIDINONE;3-BROMO-2-HYDROXY-5-METHYLPYRIDINE;TIMTEC-BB SBB003679;2-HYDROXY-3-BROMO-5-PICOLINE;3-Bromo-2-hydroxy-5-picoline;3-Bromo-2-hydroxy-5-methylpyridine 98%;3-Bromo-2-hydroxy-5-picoline 17282-02-9
• CAS NO: 17282-02-9
• Molecular Formula: C₆H₆BrNO
• Molecular Weight: 188.02
• EINECS: -0
• Product Categories: blocks;Bromides;Pyridines;Pyridine;C6Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks
• Mol File: 17282-02-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 78-82 °C(lit.)
• Boiling Point: 324 °C at 760 mmHg
• Flash Point: 149.7 °C
• Appearance: /
• Density: 1.622 g/cm³
• Vapor Pressure: 0.000253mmHg at 25°C
• Refractive Index: 1.573
• Storage Temp.: Keep Cold
• PKA: 10.95±0.10(Predicted)
• BRN: 1423374
• CAS DataBase Reference: 3-BROMO-2-HYDROXY-5-METHYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-2-HYDROXY-5-METHYLPYRIDINE(17282-02-9)
• EPA Substance Registry System: 3-BROMO-2-HYDROXY-5-METHYLPYRIDINE(17282-02-9)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-37/38-41-36/37/38
• Safety Statements: 26-36/37/39-36
• RIDADR: 1993
• WGK Germany: 3
• PackingGroup: III
• Hazardous Substances Data: 17282-02-9(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C6H6BrNO/c1-4-2-5(7)6(9)8-3-4/h2-3H,1H3,(H,8,9)

Upstream product

• 1003-68-5 5-methyl-2-pyridone 
• 1003-68-5 5-methyl-pyridin-2-ol 

Downstream Products

• 17282-03-0 3-bromo-2-chloro-5-methyl-pyridine 
• 1160358-21-3 (S)-7-(1-(4-fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-5-methyl-7H-pyrazolo[3,4-b]pyridine 
• 1083168-84-6 2-methoxy-5-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 
• 1613033-19-4 3-bromo-1-(3-(formyl)phenyl)-5-(methyl)-2(1H)-pyridinone 
• 1441005-66-8 C₁₉H₂₃BrN₂O₃ 
• 1206773-24-1 N-[4-[(E)-2-[3-tert-butyl-2-methoxy-5-(5-methyl-2-oxo-1H-pyridin-3-yl)phenyl]vinyl]phenyl]methanesulfonamide 

Relevant articles and documents

BIARYL DERIVATIVE AS GPR120 AGONIST

The present invention relates to a biaryl derivative expressed by the chemical formula 1, a method for producing the biaryl derivative, a pharmaceutical composition comprising same, and use of same, the biaryl derivative expressed by the chemical formula 1, as a GPR120 agonist, promoting GLP-1 generation in the gastro-intestinal tract, reducing insulin resistance in the liver, muscles and the like from anti-inflammatory activity in the macrophage, pancreatic cells and the like, and allowing effective use in prevention or treatment of inflammation or metabolic diseases such as diabetes, complications from diabetes, obesity, non-alcoholic fatty liver disease, fatty liver disease, and osteoporosis.

Pyridine-3-carboxamide derivatives as CB1 inverse agonists

The present invention relates to compounds of the formula wherein X and R1 to R8 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with the modulation of CB1 receptors, such as obesity.