172611-73-3

Basic information

• Product Name: DMAB-OH
• Synonyms: DMAB-OH;4-(N-[1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEXYLIDENE)-3-METHYLBUTYL]-AMINO) BENZYL ALCOHOL;2(1(4-HYDROXYME)PHE.AMINO)-3-ME.BUTYLI-;2-{1-[4-(HydroxyMethyl)phenylaMino]-3-Methylbutylidene}-5,5-diMethyl-1,3-cyclohexanedione;2-(1-((4-(Hydroxymethyl)phenyl)amino)-3-methylbutylidene)-5,5-dimethylcyclohexane-1,3-dione;Dmab-OH Novabiochem
• CAS NO: 172611-73-3
• Molecular Formula: C₂₀H₂₇NO₃
• Molecular Weight: 329.43
• Mol File: 172611-73-3.mol

Chemical Properties

• Melting Point: 156-160
• Boiling Point: 482.9°C at 760 mmHg
• Flash Point: 245.8°C
• Appearance: /
• Density: 1.132g/cm³
• Vapor Pressure: 3.91E-10mmHg at 25°C
• Refractive Index: 1.571
• Storage Temp.: 0-6°C
• CAS DataBase Reference: DMAB-OH(CAS DataBase Reference)
• NIST Chemistry Reference: DMAB-OH(172611-73-3)
• EPA Substance Registry System: DMAB-OH(172611-73-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 172611-73-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
DMAB-OH is used as a building block for the synthesis of pharmaceuticals, contributing to the development of new drugs and medicinal compounds due to its chemical properties.
Used in Fragrance Production:
As a component in the creation of fragrances, DMAB-OH is used for its sweet odor, enhancing the scent profiles of various products in the perfumery and cosmetics industries.
Used in Skin Care Product Formulation:
DMAB-OH is used as a stabilizer in skin care products to maintain their consistency and effectiveness, ensuring the longevity and quality of these formulations.
Used in Coatings and Adhesives Production:
In the manufacturing of coatings and adhesives, DMAB-OH serves as an additive to improve the performance and characteristics of these materials, such as adhesion strength and durability.
It is crucial to handle DMAB-OH with care due to its potential to cause skin and eye irritation, and its harmful effects if ingested or inhaled, highlighting the importance of safety measures in its application across various industries.

InChI:InChI=1/C20H27NO3/c1-13(2)9-16(21-15-7-5-14(12-22)6-8-15)19-17(23)10-20(3,4)11-18(19)24/h5-8,13,21-22H,9-12H2,1-4H3

Upstream product

• 623-04-1 4-aminobenzenemethanol 
• 172611-72-2 2-(1-hydroxy-3-methylbutylidene)-5,5-dimethylcyclohexane-1,3-dione 

Downstream Products

• 1357485-73-4 (2S,3S)-1-(4-(1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutylamino)benzyl) 4-benzyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(tertbutyldimethylsilyloxy)succinate 
• 863715-19-9 N-α-Fmoc-D-tyrosine 4-{N-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino}benzyl ester 
• 877843-15-7 Fmoc-Lys-ODmab 
• 863715-16-6 N-α-Fmoc-O-tert-butyl-D-tyrosine 4-{N-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino}benzyl ester 
• 359009-97-5 3-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid 4-[1-(4,4-dimethyl-2,6-dioxo-cyclohexylidene)-3-methyl-butylamino]-benzyl ester 

Relevant articles and documents

A novel 4-aminobenzyl ester-based carboxy-protecting group for synthesis of atypical peptides by Fmoc-Bu(t) solid-phase chemistry

4-{N-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino} benzyl ester (ODmab) is a new carboxy-protecting group that is based on the safety-catch principle and can be used orthogonally with Fmoc-Bu(t) peptide chemistry, but is completely removable with 2% v/v hydrazine H2O-DMF at room temperature within minutes.