171754-02-2 Usage
Description
(3S)-2-Azabicyclo(2.2.1)heptane-3-carbo, commonly known as tropanes, is a class of organic compounds characterized by a bicyclic structure with a nitrogen atom. These compounds are found in various alkaloids such as cocaine, atropine, and scopolamine. Tropanes exhibit a range of pharmacological effects, including anticholinergic, sympathomimetic, and local anesthetic properties. Due to their high potency, they have been extensively studied for potential medicinal uses, as well as their addictive and harmful effects. Furthermore, tropane derivatives have been investigated for the treatment of neurological and psychiatric disorders.
Uses
Used in Pharmaceutical Industry:
(3S)-2-Azabicyclo(2.2.1)heptane-3-carbo is used as a key component in the development of pharmaceutical agents for the treatment of various conditions. Its diverse pharmacological effects make it a valuable compound for the creation of medications targeting neurological and psychiatric disorders.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (3S)-2-Azabicyclo(2.2.1)heptane-3-carbo serves as a basis for the synthesis and modification of tropane derivatives. This allows researchers to explore new compounds with improved therapeutic potential and reduced side effects.
Used in Drug Development:
(3S)-2-Azabicyclo(2.2.1)heptane-3-carbo is utilized in drug development to create novel medications with anticholinergic, sympathomimetic, and local anesthetic properties. These compounds can be used to treat a variety of medical conditions, including respiratory issues, cardiovascular diseases, and certain types of pain.
Used in Toxicology Studies:
Due to their addictive and harmful effects, tropanes like (3S)-2-Azabicyclo(2.2.1)heptane-3-carbo are also used in toxicology studies. These studies aim to understand the mechanisms of action, potential side effects, and safe usage levels of these compounds, ensuring the development of safer and more effective medications.
Check Digit Verification of cas no
The CAS Registry Mumber 171754-02-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,1,7,5 and 4 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 171754-02:
(8*1)+(7*7)+(6*1)+(5*7)+(4*5)+(3*4)+(2*0)+(1*2)=132
132 % 10 = 2
So 171754-02-2 is a valid CAS Registry Number.
171754-02-2Relevant articles and documents
Application of polyamines and amino acid derivatives based on 2-azabicycloalkane backbone in enantioselective aldol reaction
Iwan, Dominika,Kamińska, Karolina,Wojaczyńska, El?bieta
, (2021/09/04)
Carbon–carbon bond forming reactions, such as aldol reaction and condensation, belong to extremely desired transformations as manifested by >25,000 entries in SciFinder. Their stereoselective variant requires the use of an appropriate catalyst with a stri
HEPATITIS C VIRUS INHIBITORS
-
, (2013/11/06)
The invention provides compounds of formulas (I) or (II): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of replication of the hepatitis C virus. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat hepatitis C viral infections, and processes and intermediates useful for preparing such compounds.
Synthesis of fragments of transforming growth factor alpha incorporating exo-2-azabicyclo[2,2,1 ]heptane-3-carboxylic acids as proline substitutes
Mellor, John M.
, p. 6765 - 6768 (2007/10/02)
Two novel amino acids, the enantiomers ofexo 2-azabicyclo [2,2,1]heptane-3-carboxylic acid have been independent synthesized by the aza Diels Alder reaction using a chiral auxiliary. The two acids have been advanced via solid phase synthesis to afford linear sequences, which have been cyclized to afford cyclic disulfide peptides, analogues of fragments of TGFd. The structures of these and other fragments have been firmly established.
