167998-61-0

Basic information

• Product Name: 5-bromomethylthiazole
• Synonyms: 5-(broMoMethyl)-1,3-thiazole;5-(BroMoMethyl)-Thiazole Hbr;Thiazole, 5-(bromomethyl)-
• CAS NO: 167998-61-0
• Molecular Formula: C4 H4 Br N S
• Molecular Weight: 178.05
• Product Categories: Thiazoles
• Mol File: 167998-61-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 228.6±15.0 °C(Predicted)
• Appearance: /
• Density: 1.751±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 1.97±0.10(Predicted)
• CAS DataBase Reference: 5-bromomethylthiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromomethylthiazole(167998-61-0)
• EPA Substance Registry System: 5-bromomethylthiazole(167998-61-0)

Safety Data

• Hazardous Substances Data: 167998-61-0(Hazardous Substances Data)

Usage

General Description

5-Bromomethylthiazole is a chemical compound with the formula C4H4BrNS. It is a type of thiazole compound that contains a bromine atom and a methyl group attached to the thiazole ring. This chemical is commonly used in pharmaceutical research and in the synthesis of various bioactive compounds due to its unique structural properties. It is also used as an intermediate in the production of agrochemicals and other specialty chemicals. 5-Bromomethylthiazole is known for its potential as a building block in the development of new drugs and has applications in the field of medicinal chemistry. It is also used as a reagent in organic synthesis and has shown promising results in various research studies for its potential therapeutic and biological activities.

Upstream product

• 3581-89-3 5-methylthiazole 
• 110-91-8 morpholine 
• 34241-39-9 azobisisobutyronitrile 
• 38585-74-9 thiazol-5-yl-methanol 

Downstream Products

• 933751-05-4 N-(thiazol-5-ylmethyl)methylamine 

Relevant articles and documents

Aryl imidazole derivative and application thereof

The invention relates to an aryl imidazole derivative and application thereof. The aryl imidazole derivative is a compound shown as a formula (I) in the description or pharmaceutically acceptable salt thereof. The invention also discloses application of the aryl imidazole derivative in preparation of drugs for treating cancers. The invention further discloses application of the aryl imidazole derivative in preparation of drugs for treating diseases caused by EGFR mutation.

METHYL SULFANYL PYRMIDMES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS

The present invention relates to pyrimidine derivatives of Formula (Ia) and (Ib) (including tautomers, isomers, prodrugs, and pharmaceutically acceptable salts thereof). Said compounds are useful in the treatment of pain (such as neuropathic pain), inflammation, and epilepsy (by acting as anticonvulsants). Methods of medical treatment making use of said compounds, as well as additional compounds of Formula (IIa) and (IIb), are also disclosed.

Thiazole-derived potent, highly bioavailable short duration growth hormone secretagogues

Replacement of the phenyl in 3 with a 2-pyridyl or 4-thiazolyl group resulted in increased potency in the rat pituitary cell GH release assay and in beagles.