167763-99-7Relevant articles and documents
Gold-Catalyzed Hydroarylation of N-Aryl Alkynamides for the Synthesis of 2-Quinolinones
Vacala, Taylor,Bejcek, Lauren P.,Williams, Chloé G.,Williamson, Alexandra C.,Vadola, Paul A.
, p. 2558 - 2569 (2017/03/14)
A mild method for the synthesis of 2-quinolinones via hydroarylation of N-aryl alkynamides is reported. While traditional methods have relied on the use of strong Br?nsted or Lewis acids, this report describes the development of mild reaction conditions that yield 2-quinolinones in good to excellent yield using a commercially available gold catalyst. Substrates bearing a variety of functional groups are presented, with N-substitution proving to be key to the reactivity of several substrates.
NUCLEIC ACID BINDING DYES AND USES THEREFOR
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, (2010/09/18)
The invention provides novel compounds and compositions of Formulas I and II, as well as methods of using them. The compounds can be used, for example, to quantify an amount of double stranded DNA in a sample subjected to nucleic acid amplification, or fo