16667-45-1

Basic information

• Product Name: 1-(methylamino)propan-2-ol
• Synonyms: 1-(methylamino)propan-2-ol;1-(Methylamino)-2-propanol;2-propanol, 1-(methylamino)-;Einecs 240-712-0;1-(methylamino)-2-propanol(SALTDATA: FREE);1-(Methylamino)-2-propanol HCl;1-(Methylamino)
• CAS NO: 16667-45-1
• Molecular Formula: C₄H₁₁NO
• Molecular Weight: 89.13624
• EINECS: 240-712-0
• Mol File: 16667-45-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 148.8°Cat760mmHg
• Flash Point: 67.4°C
• Appearance: /
• Density: 0.88g/cm³
• Vapor Pressure: 1.59mmHg at 25°C
• Refractive Index: 1.42
• PKA: 14.91±0.20(Predicted)
• CAS DataBase Reference: 1-(methylamino)propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(methylamino)propan-2-ol(16667-45-1)
• EPA Substance Registry System: 1-(methylamino)propan-2-ol(16667-45-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 16667-45-1(Hazardous Substances Data)

Usage

Description

1-(Methylamino)propan-2-ol is an organic compound with the chemical formula CH3NH(CH2)2CH2OH. It is a colorless liquid with a mild amine-like odor and is soluble in water. 1-(methylamino)propan-2-ol is characterized by the presence of a primary amine group (-NH2) attached to a propyl chain and a hydroxyl group (-OH) at the second carbon.

Uses

Used in the Preparation of Amphoteric Surfactants:
1-(Methylamino)propan-2-ol is used as a key intermediate in the synthesis of amphoteric surfactants containing polyoxyethylene group chains. These surfactants are valued for their mildness, biodegradability, and foaming properties, making them suitable for use in personal care products, such as shampoos, body washes, and bubble baths.
Used in the Personal Care Industry:
In the personal care industry, 1-(methylamino)propan-2-ol is used as a building block for the development of amphoteric surfactants with polyoxyethylene group chains. These surfactants contribute to the formulation of mild and effective cleansing products, providing a gentle cleansing experience for consumers while maintaining the integrity of the skin's natural barrier.
Used in the Formulation of Eco-friendly Cleaning Products:
1-(Methylamino)propan-2-ol-based amphoteric surfactants are favored for their biodegradability and low environmental impact. They are used in the formulation of eco-friendly cleaning products, such as dishwashing liquids and laundry detergents, that are designed to minimize harm to aquatic life and reduce the overall ecological footprint of household cleaning routines.

InChI:InChI=1/C4H11NO/c1-4(6)3-5-2/h4-6H,3H2,1-2H3

Upstream product

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Downstream Products

• 176711-20-9 1-[(2-amino-ethyl)-methyl-amino]-propan-2-ol 
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• 69451-73-6 Nicotinic acid 1-methyl-2-[methyl-(pyridine-3-carbonyl)-amino]-ethyl ester 
• 96825-84-2 1-[(3-Phenyl-pyridazino[4,3-c]isoquinolin-6-yl)methylamino]-2-propanol 
• 96825-94-4 1-{[3-(4-Chloro-phenyl)-pyridazino[4,3-c]isoquinolin-6-yl]-methyl-amino}-propan-2-ol 
• 96825-87-5 1-[[3-(4-methoxyphenyl)pyridazino-[4,3-c]-isoquinolin-6-yl]methylamino]-2-propanol 
• 113113-14-7 N-(2-Hydroxy-propyl)-N-methyl-N'-(5-o-tolyl-[1,3,4]thiadiazol-2-yl)-guanidine; hydrochloride 
• 87539-86-4 N-(2-hydroxypropyl)-3-(4-methoxyphenyl)-N-methyl-1,2,4-triazolo[3,4-a]phthalazin-6-amine 
• 55984-51-5 N₀nitrosomethyl-N-2-oxopropylamine 
• 124497-73-0 4,6-Dimethyl-2-phenyl-morpholin-2-ol; hydrochloride 
• 748809-77-0 2-(1-methoxyvinyl)-3,5-dimethyloxazolidine 
• 176370-13-1 1-(2-hydroxypropyl)-1-methylguanidine 
• 71112-21-5 1-[[2,6-dinitro-4-(trifluoromethyl)phenyl]methylamino]-2-propanol 
• 71112-15-7 1-[Methyl(4-methyl-2,6-dinitrophenyl)amino]-2-propanol 

Relevant articles and documents

HEPATITIS B ANTIVIRAL AGENTS

The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of at least one compound of the invention.

OXAZOLIDINES. 1. BASIC CATALYTIC DISPROPORTIONATION OF CYCLOHEXANOSPIRO-2-OXAZOLIDINES: SYNTHESIS OF N-SUBSTITUTED 4,5,6,7-TETRAHYDROINDOLES

It has been shown that the basic catalytic disproportionation of cyclohexanospiro-2-oxazolidines in the presence of potasium hydroxide or sodium methylate leads to N-substituted 4,5,6,7-tetrahydroindoles with a yield of up to 73percent.The influence of the character of substituents at the nitrogen atom of oxazolidine on the course of the reaction has been established.