160977-89-9

Basic information

• Product Name: (2S,3S,4S)-4-Isopropenyl-3-methoxycarbonylmethyl-1-trityl-pyrrolidine-2-carboxylic acid methyl ester
• Synonyms: (2S,3S,4S)-4-Isopropenyl-3-methoxycarbonylmethyl-1-trityl-pyrrolidine-2-carboxylic acid methyl ester
• CAS NO: 160977-89-9
• Molecular Weight: 483.607
• Mol File: 160977-89-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,3S,4S)-4-Isopropenyl-3-methoxycarbonylmethyl-1-trityl-pyrrolidine-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S,4S)-4-Isopropenyl-3-methoxycarbonylmethyl-1-trityl-pyrrolidine-2-carboxylic acid methyl ester(160977-89-9)
• EPA Substance Registry System: (2S,3S,4S)-4-Isopropenyl-3-methoxycarbonylmethyl-1-trityl-pyrrolidine-2-carboxylic acid methyl ester(160977-89-9)

Safety Data

• Hazardous Substances Data: 160977-89-9(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 76-83-5 trityl chloride 
• 487-79-6 (-)-kainic acid 

Downstream Products

• 173174-66-8 {(S)-1-[(2S,3S,4S)-3-(2-Benzyloxy-ethyl)-2-carbamoyl-4-isopropenyl-pyrrolidine-1-carbonyl]-3-methyl-butyl}-carbamic acid tert-butyl ester 
• 173174-65-7 (2S,3S,4S)-3-(2-Hydroxy-ethyl)-4-isopropenyl-1-trityl-pyrrolidine-2-carboxylic acid methyl ester 
• 160977-91-3 (2S,3S,4S)-3-Carboxymethyl-4-isopropenyl-1-trityl-pyrrolidine-2-carboxylic acid methyl ester 

Relevant articles and documents

Kainic Acid as Conformationally Constrained Glutamic Acid Analog in Peptide Synthesis

A synthetic protocol is described which allows the incorporation of the γ-amide (Kan) and the γ-benzyl ester and ether of kainic acid (Kai) into peptide chains as exemplified with the synthesis of the substance P (SP) analogs 5>-SP5-11, 5, Kan6>-SP5-11, 6>-SP6-11, 5, Kai(Bzl)11>-SP5-11 and 5, Kol(Bzl)11>-SP5-11.