160885-19-8Relevant articles and documents
One-pot synthesis of N-Cbz-l-BMAA and derivatives from N-Cbz-l-serine
Moura, Sidnei,Pinto, Ernani
, p. 2325 - 2327 (2007)
We report herein an asymmetric synthesis of the modified amino acid N-Cbz-l-BMAA and seven of its alkyl derivatives (2a-h) from N-Cbz-l-serine via ring-opening of the β-lactone (formed under modified Mitsunobu conditions) by different amines. This procedu
Reaction of Trimethylsilylamines with N-Cbz-L-Serine-β-Lactone: A Convenient Route to Optically Pure β-Amino-L-alanine Derivatives
Ratemi, Elaref S.,Vederas, John C.
, p. 7605 - 7608 (2007/10/02)
Trimethylsilylamines, Me3Si-NR2, react with N-Cbz-L-serine-β-lactone in acetonitrile primarily by alkyl oxygen cleavage of the lactone ring to give optically pure N-Cbz-β-amino-L-alanine derivatives in good yields.Use of halogenated sovents such as chloro