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  • 2-Naphthacenecarboxamide,1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-,(4aS,5aR,12aS)-;15866-90-7

    Cas No: 15866-90-7

  • No Data

  • 10 Metric Ton

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  • Amadis Chemical Co., Ltd.
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  • 15866-90-7 Structure
  • Basic information

    1. Product Name: Incyclinide
    2. Synonyms: Incyclinide;2-NaphthacenecarboxaMide,1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-,(4aS,5aR,12aS)-;CMT 3;COL 3;Metastat;NSC 683551
    3. CAS NO:15866-90-7
    4. Molecular Formula: C19H17NO7
    5. Molecular Weight: 371.34078
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 15866-90-7.mol
    9. Article Data: 0
  • Chemical Properties

    1. Melting Point: 228-231 °C
    2. Boiling Point: 752.8±60.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.70±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 4.50±1.00(Predicted)
    10. CAS DataBase Reference: Incyclinide(CAS DataBase Reference)
    11. NIST Chemistry Reference: Incyclinide(15866-90-7)
    12. EPA Substance Registry System: Incyclinide(15866-90-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 15866-90-7(Hazardous Substances Data)

15866-90-7 Usage

Description

Incyclinide, also known as Metastat, is a pharmaceutical compound with potential applications in various medical fields. It is an MMP (Matrix Metalloproteinase) inhibitor, which means it can regulate the activity of enzymes that break down proteins in the extracellular matrix. This property makes it a promising candidate for the treatment of various conditions and diseases.

Uses

Used in Dermatology:
Incyclinide is used as a therapeutic agent for the treatment of acne, rosacea, and other skin conditions. Its MMP-inhibiting properties help in reducing inflammation and promoting skin healing.
Used in Respiratory Medicine:
Incyclinide is used in the treatment of acute respiratory distress syndrome (ARDS) due to its potential to regulate the activity of MMPs, which can contribute to the severity of the condition.
Used in Antiviral Applications:
Incyclinide is considered a potential anti-COVID-19 drug, as it has been shown to significantly downregulate ACE2 activity. This makes it a promising candidate for the development of new treatments against the virus.
Used in Pharmaceutical Industry:
Incyclinide is used as an MMP inhibitor in the development of new drugs for various medical applications. Its ability to regulate the activity of MMPs makes it a valuable tool in the research and development of novel therapeutic agents.
Brand Name:
The brand name for Incyclinide is Metastat, which is developed and marketed by CollaGenex Pharmaceuticals.

Check Digit Verification of cas no

The CAS Registry Mumber 15866-90-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,8,6 and 6 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 15866-90:
(7*1)+(6*5)+(5*8)+(4*6)+(3*6)+(2*9)+(1*0)=137
137 % 10 = 7
So 15866-90-7 is a valid CAS Registry Number.

15866-90-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Desmethylamino-6-desmethyl-6-desoxy-tetracyclin

1.2 Other means of identification

Product number -
Other names Incyclinide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15866-90-7 SDS

15866-90-7Upstream product

15866-90-7Downstream Products

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