1569897-10-4

Basic information

• Product Name: C₁₃H₈F₃N₃
• Synonyms: C₁₃H₈F₃N₃
• CAS NO: 1569897-10-4
• Molecular Weight: 263.222
• Mol File: 1569897-10-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₃H₈F₃N₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₈F₃N₃(1569897-10-4)
• EPA Substance Registry System: C₁₃H₈F₃N₃(1569897-10-4)

Safety Data

• Hazardous Substances Data: 1569897-10-4(Hazardous Substances Data)

Upstream product

• 74784-70-6 2-amino-5-trifluoromethylpyridine 
• 100-47-0 benzonitrile 
• 50488-42-1 2-bromo-5-(trifluoromethyl)pyridine 
• 143812-60-6 6-trifluoromethyltetrazolo<1,5-a>pyridine 

Relevant articles and documents

Dual Reactivity of 1,2,3,4-Tetrazole: Manganese-Catalyzed Click Reaction and Denitrogenative Annulation

A general catalytic method using a Mn-porphyrin-based catalytic system is reported that enables two different reactions (click reaction and denitrogenative annulation) and affords two different classes of nitrogen heterocycles, 1,5-disubstituted 1,2,3-triazoles (with a pyridyl motif) and 1,2,4-triazolo-pyridines. Mechanistic investigations suggest that although the click reaction likely proceeds through an ionic mechanism, which is different from the traditional click reaction, the denitrogenative annulation reaction likely proceeds via an electrophilic metallonitrene intermediate rather than a metalloradical intermediate. Collectively, this method is highly efficient and offers several advantages over other methods. For example, this method excludes a multi-step synthesis of the N-heterocyclic molecules described and produces only environmentally benign N2 gas a by-product.