155877-06-8

Basic information

• Product Name: Tetraisopropylazodicarboxamid
• Synonyms: Tetraisopropylazodicarboxamid;Tetrakis(1-methylethyl)diazenedicarboxamide;TetraisopropylazodicarboxaMide
• CAS NO: 155877-06-8
• Molecular Formula: C14H28N4O2
• Molecular Weight: 284.39772
• Mol File: 155877-06-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 341.2±25.0 °C(Predicted)
• Appearance: /
• Density: 1.02±0.1 g/cm3(Predicted)
• PKA: -0.76±0.70(Predicted)
• CAS DataBase Reference: Tetraisopropylazodicarboxamid(CAS DataBase Reference)
• NIST Chemistry Reference: Tetraisopropylazodicarboxamid(155877-06-8)
• EPA Substance Registry System: Tetraisopropylazodicarboxamid(155877-06-8)

Safety Data

• Hazardous Substances Data: 155877-06-8(Hazardous Substances Data)

Usage

Description

Tetraisopropylazodicarboxamid, also known as TIADC, is a chemical compound characterized by the molecular formula C16H32N6O4. It is a versatile reagent in organic synthesis, especially within the domain of synthetic chemistry. TIADC is recognized for its capacity to serve as a nitrogen source in a variety of chemical reactions and is instrumental in the synthesis of heterocyclic compounds. Its utility extends to the production of pharmaceuticals and agrochemicals, making it a significant compound in the realm of organic chemistry. However, due to its high reactivity, TIADC necessitates careful handling and storage to prevent potential explosions when exposed to heat or flame.

Uses

Used in Organic Synthesis:
Tetraisopropylazodicarboxamid is used as a reagent in organic synthesis for its ability to act as a nitrogen source in various chemical reactions, facilitating the formation of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, Tetraisopropylazodicarboxamid is utilized as a key intermediate in the synthesis of various drugs, contributing to the development of new medicinal compounds.
Used in Agrochemical Production:
Similarly, in the agrochemical sector, Tetraisopropylazodicarboxamid is employed as a precursor in the production of pesticides and other agricultural chemicals, enhancing crop protection and yield.
Used in Heterocyclic Compound Preparation:
Tetraisopropylazodicarboxamid is used as a crucial component in the preparation of heterocyclic compounds, which are important in the creation of a wide range of chemical products, including pharmaceuticals and dyes.
Used in Research and Development:
In the field of research and development, Tetraisopropylazodicarboxamid is used as a tool to explore new reaction pathways and to develop innovative synthetic methods, advancing the frontiers of chemical science.

Upstream product

• 108-18-9 diisopropylamine 

Relevant articles and documents

N,N,N',N'-Tetramethylazodicarboxamide (TMAD), A New Versatile Reagent for Mitsunobu Reaction. Its Application to Synthesis of Secondary Amines

N,N,N',N'-Tetramethylazodicarboxamide, (TMAD), was found to be more versatile in the Mitsunobu reaction than traditional diethyl azodicarboxylate or recently developed 1,1'-(azodicarbonyl)dipiperidine, when used in combination with tributylphosphine in benzene.The usefulness of the reagent was demonstrated by the highly efficient two-step synthesis of benzylcrotylamine from N-benzyltrifluoroacetamide.