154325-75-4 Usage
Description
ETHYL 5-BROMO-2,2-DIMETHYL-4-OXOPENTANOATE is an indolylalkanoate intermediate with the chemical properties of a colorless oil. It is a significant compound in the field of pharmaceuticals and biochemistry due to its potential applications as a leukotriene biosynthesis inhibitor.
Uses
Used in Pharmaceutical Industry:
ETHYL 5-BROMO-2,2-DIMETHYL-4-OXOPENTANOATE is used as a leukotriene biosynthesis inhibitor for its ability to modulate the production of leukotrienes, which are inflammatory mediators involved in various diseases such as asthma and inflammatory bowel disease. By inhibiting leukotriene biosynthesis, this compound can potentially alleviate symptoms and improve the quality of life for patients suffering from these conditions.
Used in Biochemical Research:
In the field of biochemical research, ETHYL 5-BROMO-2,2-DIMETHYL-4-OXOPENTANOATE serves as an essential intermediate for the synthesis of various indolylalkanoate derivatives. These derivatives can be further studied for their potential therapeutic applications and to gain a deeper understanding of the underlying mechanisms of leukotriene biosynthesis and its role in disease processes.
Used in Drug Development:
ETHYL 5-BROMO-2,2-DIMETHYL-4-OXOPENTANOATE is also utilized in drug development as a key building block for the creation of novel therapeutic agents targeting leukotriene biosynthesis. Its unique chemical structure allows for the design and synthesis of new drugs with improved efficacy, selectivity, and safety profiles, ultimately contributing to the advancement of treatment options for various inflammatory and allergic disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 154325-75-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,3,2 and 5 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 154325-75:
(8*1)+(7*5)+(6*4)+(5*3)+(4*2)+(3*5)+(2*7)+(1*5)=124
124 % 10 = 4
So 154325-75-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H15BrO3/c1-4-13-8(12)9(2,3)5-7(11)6-10/h4-6H2,1-3H3
154325-75-4Relevant articles and documents
COMPOUNDS AND METHODS FOR TREATMENT OF HEDGEHOG PATHWAY ASSOCIATED CONDITIONS
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, (2020/01/24)
Provided herein is novel compounds of formula (I), (II), (III), (IV), and (V) as described in the specification, and pharmaceutically acceptable salts, solvates, and prodrugs and compositions thereof, and methods of measuring hedgehog pathway activation in tumor cells, examining tumor cell proliferation, differentiation and apoptosis and using the compounds and pharmaceutical compositions disclosed for treatment of diseases and disorders associated with the hedgehog signaling pathway.
A hedgehog pathway inhibitor and its preparation method and application
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, (2019/04/10)
The invention relates to a compound, the structural formula of the compound is shown as formula (1) is shown. The invention also provides a method for preparing the compound. The invention also provides the above-mentioned compound or its pharmaceutically
Compound as well as preparation method and application thereof
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, (2019/05/08)
The invention relates to a compound. The structural formula of the compound is shown as formula (1) in the description, wherein R is H or CH3. The invention further provides a preparation method of the compound and an application of the compound or pharmaceutically acceptable salt, solvate or drug complex of the compound to preparation of drugs for treating hedgehog pathway activation-related diseases. The compound can be used for preparing the drugs for treating the hedgehog pathway activation-related diseases, can well inhibit medulloblastoma growth and can be used for preparing drugs for treating medulloblastoma-related diseases.
