153439-24-8

Basic information

• Product Name: C₁₁H₁₄N₂O₅S
• CAS NO: 153439-24-8
• Molecular Weight: 286.309
• Mol File: 153439-24-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₁H₁₄N₂O₅S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₁H₁₄N₂O₅S(153439-24-8)
• EPA Substance Registry System: C₁₁H₁₄N₂O₅S(153439-24-8)

Safety Data

• Hazardous Substances Data: 153439-24-8(Hazardous Substances Data)

Upstream product

• 380885-39-2 N-(p-toluenyl)-N'-(chlorosulfonyl)-urea 
• 71254-63-2 7-methyl-3-oxo-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide 
• 609-55-2 2-amino-5-methyl-benzenesulfonamide 
• 4755-77-5 Ethyl oxalyl chloride 
• 106-49-0 p-toluidine 

Relevant articles and documents

Synthesis and pharmacological activity of N-(2,2-dimethyl-3,4-dihydro-2H-1- benzopyran-4-yl)-4H-1,2,4-benzothiadiazine-3-carboxamides 1,1-dioxides on rat uterus, rat aorta and rat pancreatic β-cells

N-(2,2-Dimethyl-3,4-dihydro-2H-1-benzopyran-4-yl)-4H-1,2, 4-benzothiadiazine-3-carboxamides 1,1-dioxides were prepared and evaluated on rat uterus, rat aortic rings and rat pancreatic β-cells. Pharmacological studies conducted on rat uterus indicated that several of these original hybrid compounds displayed a strong myorelaxant activity. The most active compounds hold a bromine atom at the 6-position of the dihydrobenzopyran ring. Moreover, the compounds failed to display a marked inhibitory effect on insulin secretion and vascular myogenic activity. These features suggest that the 6-bromo compounds could be relatively selective towards the uterine smooth muscle.