153433-26-2 Usage
Description
2-Chloro-1,3-dimethylimidazolidinium tetrafluoroborate is an organic compound that exists as a colorless to white crystalline powder. It is a versatile reagent utilized in various chemical reactions and processes, particularly in the field of organic synthesis and pharmaceutical chemistry.
Uses
Used in Organic Synthesis:
2-Chloro-1,3-dimethylimidazolidinium tetrafluoroborate is used as a reagent for the esterification of C-terminal amino acids to Wang resin without racemization. This property is crucial for maintaining the stereochemistry of the molecule, which is essential in the synthesis of biologically active compounds.
Used in Peptide Synthesis:
2-Chloro-1,3-dimethylimidazolidinium tetrafluoroborate is also employed for the coupling of sterically hindered amino acids, which are challenging to incorporate into peptides due to their bulky side chains. The use of 2-Chloro-1,3-dimethylimidazolidinium tetrafluoroborate facilitates the formation of peptide bonds in these cases, enabling the synthesis of complex peptide structures.
Used in the Preparation of Diazo-Transfer Reagents:
2-Chloro-1,3-dimethylimidazolidinium tetrafluoroborate is utilized in the preparation of efficient diazo-transfer reagents. These reagents are important in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals.
Used in Catalyst Synthesis:
The compound is also used in the oxidative insertion process for the synthesis of palladium and nickel catalysts. These catalysts are vital in numerous chemical reactions, particularly in cross-coupling reactions, which are widely used in the synthesis of complex organic molecules.
Used in Pharmaceutical Chemistry:
In the pharmaceutical industry, 2-Chloro-1,3-dimethylimidazolidinium tetrafluoroborate is used in the preparation of catalysts for coupling reactions. These catalysts are essential for the synthesis of various drug molecules, contributing to the development of new medications and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 153433-26-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,4,3 and 3 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 153433-26:
(8*1)+(7*5)+(6*3)+(5*4)+(4*3)+(3*3)+(2*2)+(1*6)=112
112 % 10 = 2
So 153433-26-2 is a valid CAS Registry Number.
InChI:InChI=1/C5H11ClN2.BF4/c1-7-3-4-8(2)5(7)6;2-1(3,4)5/h5H,3-4H2,1-2H3;/q;-1/p+1
