146860-52-8Relevant articles and documents
Concave Reagents. 12. Polymerfixation of Concave Pyridines
Luening, Ulrich,Gerst, Matthias
, p. 656 - 660 (1992)
Via a metal ion template directed synthesis and a high dilution cyclization, a bimacrocyclic 4-benzyloxyethoxy-substituted concave pyridine 8 was synthesized from dialdehyde 3, diamine 4 and diacyl dichloride 7 in 54percent overall yield.Pd-catalyzed hydrogenolysis of 8 afforded the OH-substituted concave pyridine 9 which could be attached to a Merrifield resin 10 after deprotonation with NaH.The modified polymer 11 contained 10percent (w/w) of 8.