1449399-88-5 Usage
Description
(2E)-1-(4-ethoxyphenyl)-3-(3-methylphenyl)lprop-2-en-1-one is an organic compound with a molecular formula C18H18O2. It is a ketone characterized by an ethoxyphenyl group and a 3-methylphenyl group attached to a prop-2-en-1-one functional group. (2E)-1-(4-ethoxyphenyl)-3-(3-methylphenyl)lprop-2-en-1-one is a versatile and important building block in the field of organic chemistry.
Uses
Used in Organic Synthesis:
(2E)-1-(4-ethoxyphenyl)-3-(3-methylphenyl)lprop-2-en-1-one is used as a key intermediate in organic synthesis for the production of various compounds.
Used in Pharmaceutical Industry:
(2E)-1-(4-ethoxyphenyl)-3-(3-methylphenyl)lprop-2-en-1-one is used as a key intermediate for the production of pharmaceuticals, contributing to the development of new drugs.
Used in Pesticide Industry:
(2E)-1-(4-ethoxyphenyl)-3-(3-methylphenyl)lprop-2-en-1-one is used as a key intermediate in the production of pesticides, aiding in the creation of effective pest control solutions.
Used in Fragrance Industry:
(2E)-1-(4-ethoxyphenyl)-3-(3-methylphenyl)lprop-2-en-1-one is used as a component in the fragrance industry, adding unique scents to various products.
Used in Medicinal Chemistry:
(2E)-1-(4-ethoxyphenyl)-3-(3-methylphenyl)lprop-2-en-1-one has potential applications in medicinal chemistry, where it may be utilized in the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 1449399-88-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,4,9,3,9 and 9 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1449399-88:
(9*1)+(8*4)+(7*4)+(6*9)+(5*3)+(4*9)+(3*9)+(2*8)+(1*8)=225
225 % 10 = 5
So 1449399-88-5 is a valid CAS Registry Number.
1449399-88-5Relevant articles and documents
Effects of structural and electronic characteristics of chalcones on the activation of peroxisome proliferator-activated receptor gamma
Schott, Jason Taylor,Mordaunt, Charles Edward,Vargas, Anthony Joseph,Leon, Martin Antonio,Chen, Kevin Hsinwen,Singh, Mandeep,Satoh, Mikiko,Cardenas, Emilio Leal,Maitra, Santanu,Patel, Nilay Vinod,De Lijser, Hubrecht Johan Peter
, p. 229 - 236 (2013/03/14)
Chalcones share some structural similarities with GW-1929, a highly-selective and potent agonist for peroxisome proliferator-activated receptor-gamma (PPARγ). In this study, we tested 53 structurally diverse chalcones to identify characteristics essential for PPARγ activation in a GAL4-based transactivation assay. This screen identified several novel chalcone agonists of PPARγ. Our results indicate that chalcones with an electron rich group or sterically large groups such as naphthyl on the carbonyl side tend to activate PPARγ. The absence of any strict structural or electronic requirements suggests that the flexibility of the PPARγ ligand binding pocket may allow binding of diverse chalcones with some preference for a slightly larger electron-rich group on the carbonyl side. We predict that further structure-activity relationship studies on chalcones with naphthalene or electron-rich groups near the carbonyl moiety will lead to the development of more potent PPARγ agonists.
