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1436415-49-4

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  • 1436415-49-4 Structure

  • Basic information

    1. Product Name: methyl 2-(6-ethyl-5-methoxy-4-oxo-4H-pyran-3-carbonyl)-3,5-dimethoxybenzoate
    2. Synonyms: methyl 2-(6-ethyl-5-methoxy-4-oxo-4H-pyran-3-carbonyl)-3,5-dimethoxybenzoate
    3. CAS NO:1436415-49-4
    4. Molecular Formula:
    5. Molecular Weight: 376.363
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1436415-49-4.mol
    9. Article Data: 1

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: methyl 2-(6-ethyl-5-methoxy-4-oxo-4H-pyran-3-carbonyl)-3,5-dimethoxybenzoate(CAS DataBase Reference)
    10. NIST Chemistry Reference: methyl 2-(6-ethyl-5-methoxy-4-oxo-4H-pyran-3-carbonyl)-3,5-dimethoxybenzoate(1436415-49-4)
    11. EPA Substance Registry System: methyl 2-(6-ethyl-5-methoxy-4-oxo-4H-pyran-3-carbonyl)-3,5-dimethoxybenzoate(1436415-49-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1436415-49-4(Hazardous Substances Data)

1436415-49-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1436415-49-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,3,6,4,1 and 5 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1436415-49:
(9*1)+(8*4)+(7*3)+(6*6)+(5*4)+(4*1)+(3*5)+(2*4)+(1*9)=154
154 % 10 = 4
So 1436415-49-4 is a valid CAS Registry Number.

1436415-49-4Downstream Products

1436415-49-4Relevant articles and documents

Total syntheses and biological evaluation of 3-O-methylfunicone and its derivatives prepared by TMPZnCl·LiCl-mediated halogenation and carbonylative stille cross-coupling

Ehrlich, Michael,Carell, Thomas

, p. 77 - 83 (2013/03/13)

The total syntheses of the natural product 3-O-methylfunicone (1), a member of the funicone class of compounds, and its derivatives is reported. The key reactions in the construction of the biaryl ketone core are a regioselective TMPZnCl·LiCl halogenation and a carbonylative Stille cross-coupling reaction. In addition, the inhibitory activities of the funicones against Y-family DNA polymerase κ (pol κ) and polymerase η (pol η) were determined. We found that 1 and 12 exhibit inhibitory activity against pol η and 1 also against pol κ. The total syntheses of the natural product 3-O-methylfunicone and its derivatives has been accomplished. The key reactions are TMPZnCl·LiCl-mediated iodination and a carbonylative Stille cross-coupling reaction. In addition, the inhibitory effect of the synthesized compounds have been evaluated against Y-family DNA polymerases κ and η by primer extension experiments. Copyright

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