1435489-02-3

Basic information

• Product Name: 1-methyl-6-phenyl-2-(p-tolyl)-3-(4-(trifluoromethyl)phenyl)-1H-imidazo[1,2-b]pyrazole
• Synonyms: 1-methyl-6-phenyl-2-(p-tolyl)-3-(4-(trifluoromethyl)phenyl)-1H-imidazo[1,2-b]pyrazole
• CAS NO: 1435489-02-3
• Molecular Weight: 431.46
• Mol File: 1435489-02-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-methyl-6-phenyl-2-(p-tolyl)-3-(4-(trifluoromethyl)phenyl)-1H-imidazo[1,2-b]pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-6-phenyl-2-(p-tolyl)-3-(4-(trifluoromethyl)phenyl)-1H-imidazo[1,2-b]pyrazole(1435489-02-3)
• EPA Substance Registry System: 1-methyl-6-phenyl-2-(p-tolyl)-3-(4-(trifluoromethyl)phenyl)-1H-imidazo[1,2-b]pyrazole(1435489-02-3)

Safety Data

• Hazardous Substances Data: 1435489-02-3(Hazardous Substances Data)

Upstream product

• 1435488-87-1 6-phenyl-2-(p-tolyl)-1H-imidazo[1,2-b]pyrazole hydrochloride 
• 402-52-8 methyl 4-(trifluoromethyl)phenyl ether 
• 1435488-90-6 1-methyl-6-phenyl-2-(p-tolyl)-1H-imidazo[1,2-b]pyrazole 
• 619-41-0 4-(bromoacetyl)toluene 
• 1435488-84-8 2-(5-amino-3-phenyl-1H-pyrazol-1-yl)-1-(p-tolyl)ethanone 

Relevant articles and documents

Efficient synthesis and first regioselective c-3 direct arylation of imidazo[1,2-b]pyrazoles

Highly regioselective: An efficient synthesis of the imidazo[1,2-b]pyrazole core has been developed, and the first regioselective palladium-catalyzed direct arylation of the C-3 position is described (see scheme). Good to excellent yields were obtained for a wide range of aryl partners with electron-rich and electron-poor substituents. This methodology allows rapid access to a large variety of imidazo[1,2-b]pyrazole products and could open the way to the design of new biologically active compounds. Copyright