1418140-93-8

Basic information

• Product Name: C₃₂H₂₇FN₂O₄
• Synonyms: C₃₂H₂₇FN₂O₄
• CAS NO: 1418140-93-8
• Molecular Weight: 522.576
• Mol File: 1418140-93-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₂H₂₇FN₂O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₂H₂₇FN₂O₄(1418140-93-8)
• EPA Substance Registry System: C₃₂H₂₇FN₂O₄(1418140-93-8)

Safety Data

• Hazardous Substances Data: 1418140-93-8(Hazardous Substances Data)

Upstream product

• 116621-16-0 (6-hydroxy-1H-indol-3-yl)acetic acid methyl ester 
• 113305-56-9 4-iodo-3-nitrophenol 
• 183007-32-1 4-benzyloxy-1-iodo-2-nitrobenzene 
• 183007-33-2 3-(4-benzyloxy-2-nitrophenyl)acrylic acid methyl ester 
• 183007-34-3 3-(2-amino-4-benzyloxyphenyl)acrylic acid methyl ester 
• 183007-36-5 3-(4-benzyloxy-2-formylaminophenyl)acrylic acid methyl ester 
• 183007-31-0 3-(4-benzyloxy-2-isocyanophenyl)acrylic acid methyl ester 
• 183007-38-7 (6-benzyloxy-1H-indol-3-yl)acetic acid methyl ester 
• 27874-59-5 3-phenoxazin-10-ylpropan-1-ol 
• 610-81-1 4-hydroxy-2-nitroaniline 
• 135-67-1 phenoxazine 

Relevant articles and documents

Design and synthesis of alkoxyindolyl-3-acetic acid analogs as peroxisome proliferator-activated receptor-γ/δ agonists

A series of carbazole or phenoxazine containing alkoxyindole-3-acetic acid analogs were prepared as PPARγ/δ agonists and their transactivation activities for PPAR receptor subtypes (α, γ and δ) were investigated. Structure-activity relationship studies disclosed the effect of the lipophilic tail, attaching position of the alkoxy group and N-benzyl substitution at indole. Compound 1b was the most potent for PPARδ and 3b for PPARγ. Molecular modeling suggested two different binding modes of our alkoxyindole-3-acetic acid analogs providing the insight into their PPAR activity.