1416772-63-8

Basic information

• Product Name: C₂₅H₂₈N₂O₂
• CAS NO: 1416772-63-8
• Molecular Weight: 388.51
• Mol File: 1416772-63-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₅H₂₈N₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₅H₂₈N₂O₂(1416772-63-8)
• EPA Substance Registry System: C₂₅H₂₈N₂O₂(1416772-63-8)

Safety Data

• Hazardous Substances Data: 1416772-63-8(Hazardous Substances Data)

Upstream product

• 1416772-52-5 C₂₆H₃₀N₂O 
• 500-22-1 3-pyridinecarboxaldehyde 
• 115167-43-6 methyl (Z)-2-acetamido-3-(3-pyridyl)propenoate 
• 89890-92-6 N-acetyl-(β-3-pyridyl)-α,β-dehydroalanine 
• 95200-94-5 (S)-N-acetyl-(pyridin-3-yl)alanine methyl ester 
• 112455-83-1 (S)-methyl 2-amino-3-(pyridin-3-yl)propanoate 
• 100-52-7 benzaldehyde 
• 1416772-49-0 C₂₃H₂₄N₂O₂ 
• 1416772-50-3 C₂₂H₂₄N₂O 
• 1416772-62-7 C₂₆H₃₂N₂O₃ 
• 1416772-48-9 C₂₂H₂₂N₂O 

Downstream Products

• 1416772-53-6 C₄₆H₅₇N₃O₉ 
• 1416772-65-0 C₄₆H₅₇N₃O₉ 
• 1416772-56-9 C₂₆H₃₀N₂O₃ 
• 1416772-57-0 C₃₆H₃₇F₃N₂O₅ 
• 1416772-46-7 (2R,3S,4S)-4-(dibenzylamino)-3-hydroxy-2-methyl-5-(pyridin-3-yl)pentanoic acid 

Relevant articles and documents

Synthesis and antimycobacterial activity of 2,1′-dihydropyridomycins

Dihydropyridomycins 2 and 3, which lack the characteristic enol ester moiety of the potent antimycobacterial natural product pyridomycin (1), have been prepared from L-Thr, R- and S-hydroxy isovaleric acid, and 3-pyridinecarboxaldehyde. The 2R isomer 2 shows only 4-fold lower anti-Mtb activity than 1, indicating that the enol ester moiety in the natural product is not critical for its biological activity. This finding establishes 2 as a potent and more practical lead for anti-TB drug discovery.