141417-87-0

Basic information

• Product Name: Methanimidamide, N,N'-bis(4-methoxyphenyl)-, (E)-
• CAS NO: 141417-87-0
• Molecular Formula: C15H16N2O2
• Molecular Weight: 256.304
• Mol File: 141417-87-0.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: Methanimidamide, N,N'-bis(4-methoxyphenyl)-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanimidamide, N,N'-bis(4-methoxyphenyl)-, (E)-(141417-87-0)
• EPA Substance Registry System: Methanimidamide, N,N'-bis(4-methoxyphenyl)-, (E)-(141417-87-0)

Safety Data

• Hazardous Substances Data: 141417-87-0(Hazardous Substances Data)

Upstream product

• 5470-34-8 4-methoxyformanilide 
• 104-94-9 4-methoxy-aniline 
• 100-00-5 4-chlorobenzonitrile 
• 68-12-2 N,N-dimethyl-formamide 
• 99-99-0 1-methyl-4-nitrobenzene 
• 149-73-5 trimethyl orthoformate 
• 77287-34-4 formamide 
• 122-51-0 orthoformic acid triethyl ester 
• 1188-33-6 N,N-dimethylformamide diethyl diacetal 
• 64-19-7 acetic acid 
• 1227-44-7 N,N'-bis(4-methoxyphenyl)urea 
• 2293-07-4 1-(4-methoxyphenyl)thiourea 
• 94793-46-1 N-(4-Methoxy-phenyl)-formamidine 
• 2293-07-4 (4-methoxy-phenyl)-thiourea 

Downstream Products

• 79377-22-3 N-[2-(1-ethyl-1H-[2]quinolyliden)-ethyliden]-p-anisidine; hydriodide 
• 113449-91-5 2-p-anisidinomethylene-N-(4-methoxy-phenyl)-malonamic acid ethyl ester 
• 1230-05-3 4-methoxy-N-[2-(3-methyl-3H-benzooxazol-2-ylidene)-ethylidene]-aniline 
• 1157-54-6 4-methoxy-N-[2-(3-methyl-3H-benzothiazol-2-ylidene)-ethylidene]-aniline 
• 99018-94-7 4-isobutyl-2-[2-(4-methoxy-anilino)-vinyl]-3,5-dimethyl-thiazolium; iodide 
• 109474-86-4 2-[2-(4-methoxy-anilino)-vinyl]-3,4,5-trimethyl-oxazolium; iodide 
• 109568-00-5 4-isobutyl-2-[2-(4-methoxy-anilino)-vinyl]-3,5-dimethyl-oxazolium; iodide 
• 1157-55-7 4-methoxy-N-[2-(3-methyl-3H-benzoselenazol-2-ylidene)-ethylidene]-aniline 
• 130685-72-2 4-Cyan-3-(4-methoxy-phenylamino)-benzo<4,5>thieno<2,3-c>pyridin-9,9-dioxid 
• 128799-71-3 N¹-(p-Chlorobenzoyl)-N¹,N²-di-(p-methoxyphenyl)-formamidine 
• 128799-72-4 N¹-Tosyl-N¹,N²-di(p-methoxyphenyl)-formamidine 
• 97968-72-4 1,5-Dihydro-5-(4-methoxyphenyl)-4H-pyrazolo<3,4-d>pyrimidin-4-one 
• 5470-34-8 4-methoxyformanilide 
• 5883-82-9 2-((4-methoxyphenyl)amino)-1-phenylethanone 

Relevant articles and documents

Synthetic Applications of a New Magnetic Mesoporous Nanocomposite Catalyst Fe3O4@MCM-41@NH-SO3H

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N-Heterocyclic Carbene Catalyzed Concerted Nucleophilic Aromatic Substitution of Aryl Fluorides Bearing α,β-Unsaturated Amides

Concerted nucleophilic aromatic substitution (CSNAr) has emerged as a powerful mechanistic manifold, in which nucleophilic aromatic substitution can proceed in one step without the need to form a Meisenheimer intermediate. However, all of the CSNAr reactions reported thus far require a stoichiometric strong base or activating reagent, and no catalytic variants have yet been reported. Herein, we report an N-heterocyclic carbene (NHC)-catalyzed intramolecular cyclization of acrylamides that contain a 2-fluorophenyl group on the nitrogen through a CSNAr reaction. By using this catalytic method, it is possible to synthesize an array of quinolin-2-one derivatives, which are common structural motifs in pharmaceuticals and organic materials. DFT calculations unambiguously revealed that this reaction proceeds through the concerted nucleophilic aromatic substitution of aryl fluorides, in which a stereoelectronic σ (Cipso-Cβ)→ σ*(Cipso-F) interaction critically contributes to the stabilization of the transition state for the cyclization.

Nanoporous TiO2 containing an ionic liquid bridge as an efficient and reusable catalyst for the synthesis of: N, N ′-diarylformamidines, benzoxazoles, benzothiazoles and benzimidazoles

In this work, a green and efficient procedure is reported for the preparation of N,N'-diarylformamidines, benzoxazoles, benzothiazoles, and benzimidazoles using nanoporous TiO2 containing an ionic liquid bridge. This reagent is prepared via the modification of nanoporous TiO2 with bis-3-(trimethoxysilylpropyl)-ammonium hydrogen sulfate (TiO2-[bip]-NH2+ HSO4-). The procedure gave the products in excellent yields in very short reaction times under solvent-free conditions. The reusability of the catalyst is the other important feature of the reported method.