141283-42-3

Basic information

• Product Name: 8-Nitro-2-tetrazol-5-yl-4-oxo-4H-1-benzopyran
• Synonyms: 8-Nitro-2-tetrazol-5-yl-4-oxo-4H-1-benzopyran;8-Nitro-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-4-one
• CAS NO: 141283-42-3
• Molecular Formula: C10H5N5O4
• Molecular Weight: 259.1778
• Mol File: 141283-42-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 508.7±60.0 °C(Predicted)
• Appearance: /
• Density: 1.738
• PKA: 4.82±0.10(Predicted)
• CAS DataBase Reference: 8-Nitro-2-tetrazol-5-yl-4-oxo-4H-1-benzopyran(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Nitro-2-tetrazol-5-yl-4-oxo-4H-1-benzopyran(141283-42-3)
• EPA Substance Registry System: 8-Nitro-2-tetrazol-5-yl-4-oxo-4H-1-benzopyran(141283-42-3)

Safety Data

• Hazardous Substances Data: 141283-42-3(Hazardous Substances Data)

Usage

General Description

8-Nitro-2-tetrazol-5-yl-4-oxo-4H-1-benzopyran, also known as NTB, is a chemical compound that belongs to the class of benzopyran derivatives. It is characterized by its nitro and tetrazol-5-yl substituents, as well as its 4-oxo group. NTB has been the subject of research for its potential as an antithrombotic and antiplatelet agent, as well as its photophysical properties. Additionally, NTB has been studied for its potential application in the field of materials science, particularly in the development of luminescent materials. Overall, NTB is a versatile compound with potential applications in both the pharmaceutical and materials science industries.

Upstream product

• 134138-87-7 2-carboethoxy-7-(4-(quinolin-2-yl-methoxy)phenoxymethyl)-4-oxo-4H-1-benzopyran 
• 141283-41-2 8-nitro-4-oxo-4H-1-benzopyran-2-carbonitrile 
• 110683-75-5 ethyl 8-nitro-4-oxo-4H-benzopyran-2-carboxylate 
• 161369-34-2 8-nitro-4-oxo-4H-1-benzopyran-2-carboxamide 

Downstream Products

• 110683-22-2 8-amino-4-oxo-2-(5-1H-tetrazolyl)-4H-1-benzopyran 
• 110683-23-3 8-amino-4-oxo-2-tetrazol-5-yl-4H-1-benzopyran hydrochloride 

Relevant articles and documents

Benzopyran derivatives having leukotriene-antagonistic action

The present invention relates to novel 4-oxo-4H-1-benzopyran compounds containing benzyloxymethyl, 3-phenylpropyl, or other araliphatic substituents in their 8-position. These compounds show a leukotriene-antagonistic activity. The compounds are characterized by good oral adsorption. The compounds of the present invention may be used as anti-inflammatory and antiallergic medicaments, and in the treatment of cardiovascular diseases.

QUINOLINYL-CHROMONE DERIVATIVES AND USE FOR TREATMENT OF HYPERSENSITIVE AILMENTS

This invention relates to certain quinolinyl-chromone compounds and their use as valuable pharmaceutical agents, particularly as lipoxygenase inhibitors and/or leukotriene antagonists possessing anti-inflammatory and anti-allergic properties.