1402709-74-3

Basic information

• Product Name: 3-((4-(6-chloro-2-(3-(4-methylpiperazin-1-yl)phenyl)-3H-imidazo[4,5-b]pyridin-7-yl)piperazin-1-yl)methyl)-5-methylisoxazole
• Synonyms: 3-((4-(6-chloro-2-(3-(4-methylpiperazin-1-yl)phenyl)-3H-imidazo[4,5-b]pyridin-7-yl)piperazin-1-yl)methyl)-5-methylisoxazole
• CAS NO: 1402709-74-3
• Molecular Weight: 507.038
• Mol File: 1402709-74-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-((4-(6-chloro-2-(3-(4-methylpiperazin-1-yl)phenyl)-3H-imidazo[4,5-b]pyridin-7-yl)piperazin-1-yl)methyl)-5-methylisoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-((4-(6-chloro-2-(3-(4-methylpiperazin-1-yl)phenyl)-3H-imidazo[4,5-b]pyridin-7-yl)piperazin-1-yl)methyl)-5-methylisoxazole(1402709-74-3)
• EPA Substance Registry System: 3-((4-(6-chloro-2-(3-(4-methylpiperazin-1-yl)phenyl)-3H-imidazo[4,5-b]pyridin-7-yl)piperazin-1-yl)methyl)-5-methylisoxazole(1402709-74-3)

Safety Data

• Hazardous Substances Data: 1402709-74-3(Hazardous Substances Data)

Upstream product

• 942949-34-0 5-chloro-4-[4-(5-methyl-isoxazol-3-ylmethyl)piperazin-1-yl]-3-nitro-pyridin-2-ylamine 
• 628325-62-2 3-(4-methylpiperazin-1-yl)benzaldehyde 
• 75148-49-1 3-bromobenzaldehyde diethylacetal 
• 109-01-3 1-methyl-piperazine 

Relevant articles and documents

IMIDAZOPYRIDINES AS INHIBITORS OF AURORA KINASE AND/OR FLT3

The present invention relates to compounds of formula I: wherein R1 and R2 are as defined herein, or a pharmaceutically acceptable salt or solvate thereof. The compounds of formula I are inhibitors of aurora kinase and/or FLT3. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which aurora kinase and/or FLT3 activity is implicated.