1400992-03-1

Basic information

• Product Name: 2,4,6-trihydroxy-5-((2-oxoazepan-1-yl)methyl)isophthalaldehyde
• Synonyms: 2,4,6-trihydroxy-5-((2-oxoazepan-1-yl)methyl)isophthalaldehyde
• CAS NO: 1400992-03-1
• Molecular Weight: 307.303
• Mol File: 1400992-03-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,4,6-trihydroxy-5-((2-oxoazepan-1-yl)methyl)isophthalaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-trihydroxy-5-((2-oxoazepan-1-yl)methyl)isophthalaldehyde(1400992-03-1)
• EPA Substance Registry System: 2,4,6-trihydroxy-5-((2-oxoazepan-1-yl)methyl)isophthalaldehyde(1400992-03-1)

Safety Data

• Hazardous Substances Data: 1400992-03-1(Hazardous Substances Data)

Upstream product

• 108-73-6 3,5-dihydroxyphenol 
• 2235-00-9 vinylcaprolactam 
• 50-00-0 formaldehyd 
• 4396-13-8 2,4-diformyl 2,4,6-trihydroxybenzene 

Relevant articles and documents

Ortho-amidoalkylation of phenols via tandem one-pot approach involving oxazine intermediate

A new and efficient method for ortho-amidoalkylation of phenols via Mannich-type condensation with formaldehyde and lactams using recyclable solid acid catalyst is described. This is the first report for ortho-amidoalkylation of phenols by lactams via Mannich-type condensation. LC-ESI-MS/MS based mechanistic study revealed that reaction proceeds through o-quinone methide (o-QM) and an oxazine intermediate via tandem Knoevenagel condensation, formal [4 + 2]-Diels-Alder cycloaddition and acid catalyzed oxazine ring-opening.