139272-29-0

Basic information

• Product Name: 4-Hydrazino-N-methylbenzenemethanesulfonamide
• Synonyms: 4-HYDRAZINO-N-METHYLBENZENEMETHANESULFONAMIDE(FOR SUMATRIPTAN);4-hydrazinophenyl-N-methyl-methanesulphonamide;4-Hydrazino-N-mehtyl-benzenmethanesulphonamide;p-Hydrazino-N-methylbenzenesulfonamide;4-HYDRAZINO-BENZENE METHANE SULFONAMIDEN-METHYL HCL;4-Hydrazino-N-methylbenzenemethanesulfonamide;1-(4-Hydrazinylphenyl)-N-MethylMethanesulfonaMide;4-hydrazinyl-N-methylBenzenemethanesulfonamide
• CAS NO: 139272-29-0
• Molecular Formula: C₈H₁₃N₃O₂S
• Molecular Weight: 215.27
• Mol File: 139272-29-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 427.4 °C at 760 mmHg
• Flash Point: 212.3 °C
• Appearance: /
• Density: 1.356 g/cm³
• Vapor Pressure: 1.64E-07mmHg at 25°C
• Refractive Index: 1.619
• Storage Temp.: 2-8°C
• PKA: 11.47±0.40(Predicted)
• CAS DataBase Reference: 4-Hydrazino-N-methylbenzenemethanesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Hydrazino-N-methylbenzenemethanesulfonamide(139272-29-0)
• EPA Substance Registry System: 4-Hydrazino-N-methylbenzenemethanesulfonamide(139272-29-0)

Safety Data

• Hazardous Substances Data: 139272-29-0(Hazardous Substances Data)

Usage

Description

4-Hydrazino-N-methylbenzenemethanesulfonamide is a chemical compound that belongs to the class of sulfonamides. It is a derivative of sulfonamide with a hydrazine group attached to the benzene ring, and a methyl group attached to the nitrogen atom. 4-Hydrazino-N-methylbenzenemethanesulfonamide has been studied for its potential pharmaceutical or biological activity, particularly in the field of medicinal chemistry. Its unique chemical structure suggests that it may possess interesting properties and potential for further exploration in various scientific disciplines.

Uses

Used in Pharmaceutical Development:
4-Hydrazino-N-methylbenzenemethanesulfonamide is used as a potential candidate in the development of new drugs due to its unique chemical structure and potential biological activity. Its sulfonamide and hydrazine groups may contribute to its therapeutic properties, making it a valuable compound for medicinal chemistry research.
Used in Medicinal Chemistry Research:
As a derivative of sulfonamide, 4-Hydrazino-N-methylbenzenemethanesulfonamide is used as a research tool in medicinal chemistry to study its potential interactions with biological targets and its effects on various biological processes. Its unique structure allows researchers to investigate its potential as a lead compound for the development of novel therapeutic agents.
Used in Biological Studies:
4-Hydrazino-N-methylbenzenemethanesulfonamide is used in biological studies to explore its potential effects on cellular processes and its interactions with biomolecules. Its hydrazine and methyl groups may provide insights into its binding properties and its ability to modulate biological pathways, contributing to a better understanding of its potential applications in medicine.

InChI:InChI=1/C8H13N3O2S/c1-10-14(12,13)6-7-2-4-8(11-9)5-3-7/h2-5,10-11H,6,9H2,1H3

Upstream product

• 103360-04-9 4-fluorobenzylsulfonyl chloride 
• 1064778-57-9 C₇H₇FO₃S 
• 352-11-4 1-chloromethyl-4-fluorobenzene 
• 109903-35-7 1-(4-aminophenyl)-N-methylmethanesulfonamide 

Downstream Products

• 88919-22-6 3-(2-aminoethyl)-1H-indole-5-yl-N-methyl methane sulphonamide 
• 88919-51-1 N-methyl-2-[5-[[(methylamino)sulphonyl]methyl]-1H-indol-3-yl]ethanamine 
• 1338815-24-9 1-(4-(5-amino-3-tert-butyl-1H-pyrazol-1-yl)phenyl)-N-methyl methanesulfonamide 
• 1234737-40-6 1-[4-[(methylaminosulfonyl)methyl]phenyl]-1H-pyrazole-4-carboxamide 
• 103628-46-2 sumatripan 

Relevant articles and documents

4-Hydroxy-2-Methyl-3(2H)-Isothiazolone-1,1-Dioxide as Protecting Group of 4-(N-Methylaminosulfonyl)methylphenylhydrazine during Fischer Indole Synthesis

Protection of the benzylic position of 4-methylaminosulfonylmethylphenyl hydrazine 6 with a 4-hydroxy-2-methyl-3(2H)-isothiazolone-1,1-dioxide group allowed the preparation of indole 3 without formation of side-product.

RESPIRATORY FORMULATIONS AND COMPOUNDS FOR USE THEREIN

The present invention relates to respiratory formulations comprising a compound of formula (I): and use of said compounds and compositions in treatment, for example in the treatment of an inflammatory disease or a respiratory disorder, in particular an inflammatory mediated and/or virally mediated respiratory disorder such as asthma and COPD or the treatment or prevention of viral infection, for example infection by influenza virus, rhinovirus or RSV. The invention also extends to certain novel compounds of formula (I).

RESPIRATORY FORMULATIONS AND COMPOUNDS FOR USE THEREIN

The present invention relates to respiratory formulations comprising a compound of formula (I): and use of said compounds and compositions in treatment, for example in the treatment of an inflammatory disease or a respiratory disorder, in particular an inflammatory mediated and/or virally mediated respiratory disorder such as asthma and COPD or the treatment or prevention of viral infection, for example infection by influenza virus, rhinovirus or RSV. The invention also extends to certain novel compounds of formula (I).