13925-06-9

Basic information

• Product Name: 2-ISOBUTYL-3-METHYLPYRAZINE
• Synonyms: FEMA NUMBER 3133;FEMA 3133;2-ISOBUTYL-3-METHYLPYRAZINE;2-METHYL-3-ISOBUTYLPYRAZINE;2-methyl-3-(2-methylpropyl)-pyrazin;2-methyl-3-(2-methylpropyl)-Pyrazine;2-ISOBUTYL-3-METHYLPYRAZINE 99+%;Pyrazine, 2-methyl-3-(2-methylpropyl)-
• CAS NO: 13925-06-9
• Molecular Formula: C₉H₁₄N₂
• Molecular Weight: 150.22
• EINECS: 237-693-6
• Product Categories: Mono- & Polyalkylpyrazines;Pyrazines;Alphabetical Listings;Flavors and Fragrances;I-L
• Mol File: 13925-06-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 74 °C
• Boiling Point: 199 °C(lit.)
• Flash Point: 180 °F
• Appearance: Colorless crystal
• Density: 0.942 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.302mmHg at 25°C
• Refractive Index: n20/D 1.492(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 1.88±0.10(Predicted)
• CAS DataBase Reference: 2-ISOBUTYL-3-METHYLPYRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ISOBUTYL-3-METHYLPYRAZINE(13925-06-9)
• EPA Substance Registry System: 2-ISOBUTYL-3-METHYLPYRAZINE(13925-06-9)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 13925-06-9(Hazardous Substances Data)

Usage

Description

2-Isobutyl-3-methylpyrazine is a synthetic compound that is created through the condensation of ethylenediamine with 5-methyl-2,3-hexanedione. It is a liquid with extremely powerful herbaceous, green, and earthy notes, and it has a characteristic odor of green bell peppers. 2-ISOBUTYL-3-METHYLPYRAZINE is known for its extremely low aroma threshold values, with a detection range of 13 to 35 ppb.

Uses

Used in Flavor and Fragrance Industry:
2-Isobutyl-3-methylpyrazine is used as a flavoring agent for its powerful herbaceous, green, and earthy notes. It is particularly effective in enhancing the taste and aroma of various food products, such as coffee, potato products, cooked beef, fried cured pork, and roasted peanuts.
Used in Perfumery:
2-Isobutyl-3-methylpyrazine is also used as a fragrance ingredient in the perfumery industry. Its characteristic odor of green bell peppers can add a unique and fresh scent to various perfumes and colognes.
Used in Chemical Research:
Due to its unique chemical properties and extremely low aroma threshold values, 2-Isobutyl-3-methylpyrazine is also used in chemical research for studying the effects of various compounds on human olfactory perception and for developing new methods of flavor and fragrance synthesis.

Preparation

By condensation of ethylenediamine with 5-methyl-2,3-hexandione

InChI:InChI=1/C9H14N2/c1-7(2)6-9-8(3)10-4-5-11-9/h4-5,7H,6H2,1-3H3

Upstream product

• 71700-40-8 N-<3-(5-methyl-2-oxohexyl)>-N-phenyltriflamide 
• 107-15-3 ethylenediamine 

Downstream Products

• 109243-36-9 2-(2-hydroxy-2-phenylethyl)-3-isobutylpyrazine 

Relevant articles and documents

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Synthesis and pyrolysis of two flavor precursors of oct-1-en-3-yl methylpyrazinecarboxylates

To rich flavor additive species of pyrazines, two new compounds of 3,6-dimethyl-2,5-pyrazinedicarboxylic acid 1-octen-3-yl ester (DMPOE) and 3,5,6-trimethyl-2-pyrazinecarboxylic acid 1-octen-3-yl ester (TMPOE) were synthesized by KMnO4 oxidatio

Application of N-Phenyltrifluoromethanesulfonamides to the Synthesis of Pyrazines

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