137512-74-4 Usage
Uses
Used in Agricultural Industry:
(4''R)-4''-DEOXY-4''-(METHYLAMINO)AVERMECTIN B1 BENZOATE is used as an insecticide for controlling pests in agriculture. It is particularly effective against lepidopteran larvae, which are the caterpillar stage of various butterfly and moth species, as well as certain other insects that can cause significant damage to crops.
Used in Environmental Pest Control:
(4''R)-4''-DEOXY-4''-(METHYLAMINO)AVERMECTIN B1 BENZOATE is also used in environmental pest control to manage insect populations that can cause damage to plants, trees, and other vegetation. Its broad-spectrum activity makes it a valuable tool for protecting the health and appearance of landscapes and gardens.
Used in Veterinary Medicine:
In addition to its use in agriculture and environmental pest control, (4''R)-4''-DEOXY-4''-(METHYLAMINO)AVERMECTIN B1 BENZOATE is utilized in veterinary medicine for the treatment and prevention of various parasitic infections in animals. Its effectiveness against a wide range of insects makes it a valuable asset in maintaining the health of livestock and pets.
Metabolic pathway
In laboratory studies, emamectin benzoate is relatively stable to aqueous
hydrolysis (acid, neutral and alkaline) under dark conditions. Emamectin
benzoate degrades extensively in soil via microbial action to multiple
degradation products including the 8a-oxidation and 8a-hydroxylation
products. CO2 and soil-bound residues were the major terminal residues
which are incorporated into humic and fulvic acid fractions. In plants,
emamectin benzoate degrades extensively to multiple polar components
including the N-demethylated, N-formylated and conjugated products.
Probably due to rapid elimination in faeces, the metabolic transformation
of emamectin benzoate in animals is minimal. However, N-demethylation
was observed as the major metabolic pathway. The hydrolytic, photolytic
and overall metabolic pathways of emamectin benzoate in soils, plants
and animals are presented in Schemes 1,2 and 3.
Degradation
Emamectin benzoate (1) was relatively stable to hydrolysis in acidic, neutral
and alkaline solutions (pH 5, 7 and 9) at 25 °C, with less than 10%
degradation occurring after 30 days. It hydrolysed most rapidly in acidic
solution (pH 5) at 25 °C with a DT50 of 136 days (Chukwudebe, 1992). Two
polar components (each <10%) eluted close to the void volume under
reversed phase chromatographic conditions.
The photodegradation half-lives of emamectin benzoate (10-12 mg 1-1)
in buffered distilled water (pH 7) containing 1% (v/v) acetonitrile, ethanol
or acetone as cosolvent under continuous exposure to a xenon lamp
were 65,9 and 0.5 days, respectively. In both buffered and natural pond
water, the major photodegradation products included 8,9-MAB1a (2), 8a-hydroxylated
MAB1a (3) and minor unknown polar residues (Scheme 1).
In sensitised buffered water, 8a-oxo-MAB1a (4) and 10,11-14,15-MAB1a
diepoxide (5) were found as additional residual products (Mushtaq et al.,
1997).
Check Digit Verification of cas no
The CAS Registry Mumber 137512-74-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,5,1 and 2 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 137512-74:
(8*1)+(7*3)+(6*7)+(5*5)+(4*1)+(3*2)+(2*7)+(1*4)=124
124 % 10 = 4
So 137512-74-4 is a valid CAS Registry Number.
InChI:InChI=1/C49H75NO13.C7H6O2/c1-12-26(2)44-29(5)18-19-48(63-44)24-35-21-34(62-48)17-16-28(4)43(27(3)14-13-15-33-25-56-46-42(51)30(6)20-36(47(52)59-35)49(33,46)53)60-40-23-38(55-11)45(32(8)58-40)61-39-22-37(54-10)41(50-9)31(7)57-39;8-7(9)6-4-2-1-3-5-6/h13-16,18-20,26-27,29,31-32,34-46,50-51,53H,12,17,21-25H2,1-11H3;1-5H,(H,8,9)/b14-13+,28-16+,33-15+;/t26?,27-,29-,31-,32-,34+,35-,36-,37-,38-,39?,40?,41-,42+,43-,44+,45-,46+,48+,49+;/m0./s1
