13686-33-4 Usage
Description
Tert-butyl azide, with the chemical formula (CH3)3CN3, is a highly reactive and explosive organic azide. It is widely used in organic synthesis and chemical research due to its ability to undergo diazo transfer and participate in Huisgen cycloaddition reactions. Tert-butyl azide is also utilized in the preparation of various azido compounds. However, its explosive nature and potential hazards require extreme caution and handling only by trained personnel in a properly equipped laboratory.
Uses
Used in Organic Synthesis:
Tert-butyl azide is used as a reagent in organic synthesis for its ability to undergo diazo transfer, which is a key step in the formation of various organic compounds.
Used in Chemical Research:
In chemical research, tert-butyl azide is employed as a valuable tool for studying the properties and reactions of azide compounds, as well as for exploring new synthetic pathways and methodologies.
Used in Huisgen Cycloaddition Reactions:
Tert-butyl azide is used as a reactant in Huisgen cycloaddition reactions, which are a type of 1,3-dipolar cycloaddition involving azides and alkynes. This reaction is widely used in the synthesis of various heterocyclic compounds, including triazoles, which have diverse applications in pharmaceuticals, materials science, and bioconjugation.
Used in Preparation of Azido Compounds:
Tert-butyl azide is utilized as a precursor in the preparation of a variety of azido compounds, which are important intermediates in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Safety and Hazard Management:
Due to its explosive nature and potential hazards, tert-butyl azide is used in the development and implementation of safety protocols and hazard management strategies in chemical laboratories, ensuring the safe handling and disposal of this highly reactive compound.
Check Digit Verification of cas no
The CAS Registry Mumber 13686-33-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,6,8 and 6 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 13686-33:
(7*1)+(6*3)+(5*6)+(4*8)+(3*6)+(2*3)+(1*3)=114
114 % 10 = 4
So 13686-33-4 is a valid CAS Registry Number.
InChI:InChI=1/C4H9N3/c1-4(2,3)6-7-5/h1-3H3
13686-33-4Relevant articles and documents
tert-Butyl Cation Formation in the Hydrolysis of 2-Methyl-2-propanesulfonyl Chloride, the Simplest Tertiary Alkanesulfonyl Chloride
King, James F.,Lam, Joe Y. L.,Dave, Vinod
, p. 2831 - 2834 (2007/10/02)
Evidence is presented that only significant reaction of 2-methyl-2-propanesulfonyl chloride (1) (a) in water over the pH range 3.5-13.0 or (b) in methanol-chloroform-d is an ionization to the tert-butyl cation (2) and the chlorosulfite anion (ClSO2(-)), followed by further reactions of these species.The organic products include isobutylene (3), tert-butyl chloride (4a), tert-butyl alcohol (4b), and, at high pH, 2-methyl-2-propanesulfinate anion (6) and small amounts of 2-methyl-2-propanesulfonate anion (5).In the presence of barium chloride the rate of hydrolysis of 1 is constant over the pH range 3.5-12.0.
