1360651-30-4

Basic information

• Product Name: 6-(trifluoromethyl)-3,4-diphenylisoquinolin-1(2H)-one
• Synonyms: 6-(trifluoromethyl)-3,4-diphenylisoquinolin-1(2H)-one
• CAS NO: 1360651-30-4
• Molecular Weight: 365.354
• Mol File: 1360651-30-4.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 6-(trifluoromethyl)-3,4-diphenylisoquinolin-1(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(trifluoromethyl)-3,4-diphenylisoquinolin-1(2H)-one(1360651-30-4)
• EPA Substance Registry System: 6-(trifluoromethyl)-3,4-diphenylisoquinolin-1(2H)-one(1360651-30-4)

Safety Data

• Hazardous Substances Data: 1360651-30-4(Hazardous Substances Data)

Upstream product

• 72755-10-3 4-bromo-N-methoxybenzamide 
• 1328746-00-4 N-methoxy-4-(trifluoromethyl)benzamide 
• 501-65-5 diphenyl acetylene 
• 24056-08-4 N-methoxy-4-methoxylbenzamide 
• 455-24-3 4-trifluoromethylbenzoic acid 
• 329-15-7 4-trifluoromethyl-phenyl acetyl chloride 
• 49541-89-1 4-(trifluoromethyl)benzoyl azide 
• 40069-07-6 N-hydroxy-4-(trifluoromethyl)benzamide 
• 2967-66-0 methyl 4-(trifluoromethyl)benzoate 
• 339-59-3 4-(trifluoromethyl)benzoic acid hydrazide 

Relevant articles and documents

N-Iminopyridinium ylide-directed, cobalt-catalysed coupling of sp2C-H bonds with alkynes

N-Iminopyridinium ylides are competent monodentate directing groups for cobalt-catalysed annulation of sp2C-H bonds with internal alkynes. The pyridine moiety in the ylide serves as an internal oxidant and is cleaved during the reaction. The annulation reactions possess excellent compatibility with heterocyclic substrates, tolerating furan, thiophene, pyridine, pyrrole, pyrazole, and indole functionalities.

Synthesis of isoquinolone via rhodium(III)-catalyzed C-H activation with 1,4,2-dioxazol-5-ones as oxidizing directing group

An efficient rhodium-catalyzed direct C-H activation for the synthesis of isoquinolone with 1,4,2-dioxazol-5-ones as oxidizing directing groups have been developed, which featured mild reaction conditions, short reaction time and satisfactory yield.

Cobalt-Catalyzed Cyclization of N-Methoxy Benzamides with Alkynes using an Internal Oxidant through C-H/N-O Bond Activation

The cyclization of substituted N-methoxy benzamides with alkynes in the presence of an easily affordable cobalt complex and NaOAc provides isoquinolone derivatives in good to excellent yields. The cyclization reaction is compatible with a range of functio