13553-40-7Relevant articles and documents
Highly Selective Nonenzymatic Chiral Induction into 3-Methylglutaric Acid and cis-4-Cyclohexen-1,2-ylenebis(acetic acid) Utilizing a Functional Five-Membered Heterocycle 4(R)-MCTT
Nagao, Yoshimitsu,Ikeda, Takao,Inoue, Takehisa,Yagi, Masahiro,Shiro, Motoo,Fujita, Eiichi
, p. 4072 - 4080 (2007/10/02)
Diamide 8, prepared by treatment of 3-methylglutaric acid (1) with 4(R)-MCTT (5) in the presence of DCC in pyridine, was subjected to aminolysis with 1 equiv of piperidine in CH2Cl2 at -30 deg C to give a mixture of diastereomers 9a and 10a in a 88:12 rat