13433-42-6

Basic information

• Product Name: DIMETHYL TRIMETHYLSILYLMETHYLPHOSPHONATE
• Synonyms: DIMETHYL TRIMETHYLSILYLMETHYLPHOSPHONATE;[(Trimethylsilyl)methyl]-phosphonic acid dimethyl ester
• CAS NO: 13433-42-6
• Molecular Formula: C₆H₁₇O₃PSi
• Molecular Weight: 196.26
• Mol File: 13433-42-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 111-114 °C21.5 mm Hg(lit.)
• Flash Point: 160 °F
• Appearance: /
• Density: 1.024 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.131mmHg at 25°C
• Refractive Index: n20/D 1.435(lit.)
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: DIMETHYL TRIMETHYLSILYLMETHYLPHOSPHONATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL TRIMETHYLSILYLMETHYLPHOSPHONATE(13433-42-6)
• EPA Substance Registry System: DIMETHYL TRIMETHYLSILYLMETHYLPHOSPHONATE(13433-42-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 13433-42-6(Hazardous Substances Data)

Usage

Uses

Used in Scientific Research:
DIMETHYL TRIMETHYLSILYLMETHYLPHOSPHONATE is used as a research compound for various scientific studies and experiments. Its unique molecular structure allows researchers to explore its potential applications and interactions with other compounds.
Used in Industrial Applications:
DIMETHYL TRIMETHYLSILYLMETHYLPHOSPHONATE is used as a chemical intermediate or reagent in certain industrial processes. Its specific role may vary depending on the industry and the desired outcome, but its presence can contribute to the development of new products or the improvement of existing ones.

InChI:InChI=1/C6H17O3PSi/c1-8-10(7,9-2)6-11(3,4)5/h6H2,1-5H3

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 756-79-6 dimethyl methane phosphonate 
• 2344-80-1 Chloromethyltrimethylsilane 
• 121-45-9 phosphorous acid trimethyl ester 
• 67-56-1 methanol 
• 13433-51-7 (trimethylsilanyl-methyl)-phosphonic acid-dichloride 

Downstream Products

• 868-85-9 Dimethyl phosphite 
• 1015-28-7 dimethyl (2-oxo-2-phenylethyl)phosphonate 
• 104227-38-5 methyl 6-(dimethoxyphosphoryl)-5-oxohexanoate 
• 1615248-82-2 dmethyl (E)-2-(4-methylphenyl)-1-(trimethylsilyl)vinylphosphonate 
• 1615248-83-3 dimethyl (Z)-2-(4-methylphenyl)-1-(trimethylsilyl)vinylphosphonate 
• 1615248-81-1 dimethyl (E)-2-phenyl-1-(trimethylsilyl)vinylphosphonate 
• 1615248-85-5 dimethyl (Z)-2-(4-methoxyphenyl)-1-(trimethylsilyl)vinylphosphonate 
• 1615248-84-4 dimethyl (E)-2-(4-methoxyphenyl)-1-(trimethylsilyl)vinylphosphonate 
• 1615248-95-7 (Z)-4-isopropenyl-1-(2-(dimethylphosphono)-2-(trimethylsilylvinyl))cyclohexene 
• 1615248-94-6 (E)-4-isopropenyl-1-(2-(dimethylphosphono)-2-(trimethylsilylvinyl))cyclohexene 
• 1615248-92-4 dimethyl (1E,3E)-4-(4-methoxyphenyl)-1-(trimethylsilyl)-1,3-butadienylphosphonate 
• 1615248-93-5 dimethyl (1Z,3E)-4-(4-methoxyphenyl)-1-(trimethylsilyl)-1,3-butadienylphosphonate 
• 538-58-9 1,5-diphenyl-1,4-pentadien-3-one 
• 1392501-19-7 C₂₀H₂₂O₃ 

Relevant articles and documents

Chemoselective synthesis of β-ketophosphonates using lithiated α-(trimethylsilyl)methylphosphonate

A highly chemoselective synthesis of β-ketophosphonates from pentafluorophenyl esters and lithiated methyl α-(trimethylsilyl)methylphosphonate has been developed. This mild lithiated phosphonate reagent allows the synthesis of functionalized β-ketophosphonates in the presence of unactivated esters with high yields. This method has been compared with the standard lithiated methylphosphonate reagent.

Convenient synthesis of 1-(Trimethylsilyl)-and 1-(Trimethylstannyl) vinylphosphonates

(Equation present) Dimethyl 1,1-bis(trimethylsilyl)methylphosphonate and dimethyl 1-(trimethylsilyl)-1-(trimethylstannyl)methylphosphonate were succeeded to react with aromatic aldehydes in the presence of methyl benzoate as additive to give the correspon

Fluoride Ion-Induced Horner-Emmons Reaction of α-Silylalkylphosphonic Derivatives with Carbonyl Compounds

Dimethyl α-trimethylsilylbenzylphosphonate was allowed to react with carbonyl compounds in the presence of fluoride ion to give the corresponding olefins in fairly good yields.Use of CsF in tetrahydrofuran gave the best result.On the other hand, dimethyl trimethylsilylmethylphosphonate was allowed to react similarly with benzophenone to afford 1,1-diphenylethylene, dimethyl methylphosphonate, and dimethyl 2,2-diphenylethenylphosphonate.A similar result was obtained by using O,O-diethyl trimethylsilylmethylphophonothioate.But, reaction of trimethylsilylmethylphosphonic bis(diethylamide) afforded only the protodesilylation product.

A One Step Generation of α-Lithiotrimethylsilylalkanephosphonates. A New Preparative Route to Dialkyl 1-(Trimethylsilyl)alkanephosphonates and Vinylphosphonates

Chlorotrimethylsilane phosphonoalkylation in the presence of lithium diisopropylamide (LDA) in excess leads to the generation of an α-silyl α-phosphonyl carbanion which can be protonated, alkylated or converted into vinylphosphonates.