1339879-91-2

Basic information

• Product Name: Methyl 3-(benzyloxy)-5-((2,4-difluorobenzyl)carbamoyl)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2-carboxylate
• Synonyms: Methyl 3-(benzyloxy)-5-((2,4-difluorobenzyl)carbamoyl)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2-carboxylate;(4R,12aS)-3,4,6,8,12,12a-Hexahydro-4-methyl-6,8-dioxo-7-(phenylmethoxy)-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid
• CAS NO: 1339879-91-2
• Molecular Formula: C₂₀H₂₀N₂O₆
• Molecular Weight: 516.4906464
• Mol File: 1339879-91-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methyl 3-(benzyloxy)-5-((2,4-difluorobenzyl)carbamoyl)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 3-(benzyloxy)-5-((2,4-difluorobenzyl)carbamoyl)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2-carboxylate(1339879-91-2)
• EPA Substance Registry System: Methyl 3-(benzyloxy)-5-((2,4-difluorobenzyl)carbamoyl)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2-carboxylate(1339879-91-2)

Safety Data

• Hazardous Substances Data: 1339879-91-2(Hazardous Substances Data)

Usage

Description

Methyl 3-(benzyloxy)-5-((2,4-difluorobenzyl)carbamoyl)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2-carboxylate is a complex organic compound characterized by its unique molecular structure. It is a derivative of pyridine, a heterocyclic compound with potential applications in various fields due to its specific functional groups and structural features.

Uses

Used in Pharmaceutical Industry:
Methyl 3-(benzyloxy)-5-((2,4-difluorobenzyl)carbamoyl)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2-carboxylate is used as an intermediate in the synthesis of pharmaceutical compounds. Its unique structure allows it to serve as a building block for the development of new drugs, particularly those targeting specific biological receptors or enzymes.
Used in Antiviral Applications:
In the pharmaceutical industry, Methyl 3-(benzyloxy)-5-((2,4-difluorobenzyl)carbamoyl)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2-carboxylate is used as an antiviral agent. It has been identified as a Dolutegravir (D528800) intermediate, which is a second-generation HIV-1 integrase strand transfer inhibitor. Methyl 3-(benzyloxy)-5-((2,4-difluorobenzyl)carbamoyl)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2-carboxylate plays a crucial role in the development of new antiviral drugs to combat HIV-1 infections.
Used in Drug Delivery Systems:
Methyl 3-(benzyloxy)-5-((2,4-difluorobenzyl)carbamoyl)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2-carboxylate can also be utilized in the development of drug delivery systems. Its structural properties may allow for the creation of novel carriers or enhancers that improve the bioavailability and efficacy of various pharmaceutical compounds.

Upstream product

• 727382-68-5 4-benzyloxy-2-(1-dimethylaminomethylidene)-3-oxo-butyric acid ethyl ester 
• 19810-31-2 Benzyloxyacetyl chloride 
• 1246616-86-3 diethyl 3-(benzyloxy)-4-oxo-4H-pyran-2,5-dicarboxylate 
• 67354-34-1 ethyl 4-benzyloxyacetoacetate 
• 100-51-6 benzyl alcohol 
• 1357289-04-3 (4R,12aS)-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-7-(phenylmethoxy)-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid ethyl ester 
• 1246616-87-4 C₂₀H₂₁NO₇ 
• 1246616-84-1 C₂₂H₂₇NO₈ 
• 1246616-83-0 C₁₈H₁₉NO₆ 
• 1339879-88-7 C₃₂H₃₃F₂N₃O₇ 
• 1206102-11-5 (4R,12aS)-7-(benzyloxy)-N-(2,4-difluorobenzyl)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1′,2’:4,5]-pyrazino[2,1-b][1,3]oxazine-9-carboxamide 

Downstream Products

• 1339879-93-4 C₂₇H₃₃N₃O₅ 
• 1339879-96-7 C₂₅H₂₅N₃O₅S 
• 1206102-11-5 (4R,12aS)-7-(benzyloxy)-N-(2,4-difluorobenzyl)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1′,2’:4,5]-pyrazino[2,1-b][1,3]oxazine-9-carboxamide 
• 1051375-16-6 dolutegravir 

Relevant articles and documents

DOLUTEGRAVIR SALTS

Dolutegravir potassium salt and solid state forms thereof are provided, as well as methods of making and interconverting these forms. The Dolutegravir potassium forms, and pharmaceutical compositions containing them, may be used to treat subjects in need

PYRIDONE DERIVATIVE HAVING INTEGRASE INHIBITORY ACTIVITY

An object of the present invention is to provide a novel integrase inhibitor. The present invention relates to a novel compound having an antiviral effect, more specifically, a pyridone derivative having HIV integrase inhibitory activity, and a medicament