13300-09-9

Basic information

• Product Name: 4-methyl-6-phenylpyridazin-3(2H)-one
• Synonyms: 4-methyl-6-phenylpyridazin-3(2H)-one;4-Methyl-6-phenyl-2,3-dihydropyridazine-3-one;4-Methyl-6-phenyl-3(2H)-pyridazinone;Einecs 236-322-5;4-methyl-6-phenylpyridazine-3(2H)-one;5-methyl-3-phenyl-1H-pyridazin-6-one;4-Methyl-6-phenyl-2H-pyridazin-3-one
• CAS NO: 13300-09-9
• Molecular Formula: C₁₁H₁₀N₂O
• Molecular Weight: 186.2099
• EINECS: 236-322-5
• Mol File: 13300-09-9.mol
• Article Data: 18

Chemical Properties

• Appearance: /
• Density: 1.17 g/cm³
• Refractive Index: 1.609
• CAS DataBase Reference: 4-methyl-6-phenylpyridazin-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-6-phenylpyridazin-3(2H)-one(13300-09-9)
• EPA Substance Registry System: 4-methyl-6-phenylpyridazin-3(2H)-one(13300-09-9)

Safety Data

• Hazardous Substances Data: 13300-09-9(Hazardous Substances Data)

Usage

General Description

4-methyl-6-phenylpyridazin-3(2H)-one is a chemical compound with the molecular formula C12H10N2O. It belongs to the pyridazinone family and is characterized by a pyridazinone core with a methyl and phenyl group attached to it. 4-methyl-6-phenylpyridazin-3(2H)-one has potential applications in the field of pharmaceuticals and agrochemicals due to its unique structure and properties. It may also have potential uses in organic synthesis as a building block for the preparation of various other compounds. Additionally, 4-methyl-6-phenylpyridazin-3(2H)-one has been studied for its biological activity and potential medicinal properties, making it an interesting target for further research and development.

InChI:InChI=1/C11H10N2O/c1-8-7-10(12-13-11(8)14)9-5-3-2-4-6-9/h2-7H,1H3,(H,13,14)

Upstream product

• 15732-75-9 3-benzoyl-2-methylenepropionic acid 
• 50-00-0 formaldehyd 
• 266001-35-8 4-diethoxyphosphoryl-6-phenylpyridazin-3(2H)-one 
• 71-43-2 benzene 
• 28657-39-8 3-chloro-4-methyl-6-phenylpyridazine 
• 98-80-6 phenylboronic acid 
• 4578-42-1 3-methoxy-6-phenylpyridazine 
• 2170-03-8 itaconic acid anhydride 
• 5754-18-7 4-methyl-1,2-dihydropyridazine-3,6-dione 
• 1771-65-9 2-methyl-4-oxo-4-phenylbutanoic acid 
• 52239-91-5 4-methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one 
• 148903-67-7 β-benzoyl-2-methylenepropionic acid methyl ester 
• 13299-97-3 acide α-methyl β-benzoyl lactique 
• 81819-89-8 3-Butoxy-4-methyl-6-phenyl-pyridazine 

Downstream Products

• 13299-75-7 4-methyl-2-(1-methyl-2-morpholin-4-yl-ethyl)-6-phenyl-2H-pyridazin-3-one 
• 924909-75-1 TT-302 
• 30321-87-0 (5-methyl-6-oxo-3-phenyl-6H-pyridazin-1-yl)-acetic acid ethyl ester 
• 1450829-19-2 2-[5-methyl-6-oxo-3-phenylpyridazin-1(6H)-yl]acetic acid 
• 1450829-22-7 N-(1,3-benzodioxol-5-yl)-2-[5-methyl-6-oxo-3-phenylpyridazin-1(6H)-yl]acetamide 
• 1450829-21-6 N-(4-fluorophenyl)-2-[5-methyl-6-oxo-3-phenylpyridazin-1(6H)-yl]acetamide 
• 1450829-20-5 N-(4-bromophenyl)-2-[5-methyl-6-oxo-3-phenylpyridazin-1(6H)-yl]acetamide 
• 66573-63-5 8-methyl-6-phenyl-[1,2,4]triazolo[4,3-b]pyridazine 
• 90746-29-5 3-bromo-4-methyl-6-phenylpyridazine 
• 898820-55-8 3-bromo-4-(bromomethyl)-6-phenylpyridazine 
• 32723-48-1 3-hydrazino-4-methyl-6-phenyl-pyridazine 
• 105537-56-2 2-(carboxymethyl)-3-amino-4-methyl-6-phenylpyridazinium acetate 
• 105537-95-9 6-Amino-1-(3-ethoxycarbonyl-1-methyl-propyl)-5-methyl-3-phenyl-pyridazin-1-ium; bromide 
• 105537-93-7 ethyl ester of 2-(5-carboxypentyl)-3-amino-4-methyl-6-phenylpyridazinium bromide 

Relevant articles and documents

Development of a novel therapeutic suppressor of brain proinflammatory cytokine up-regulation that attenuates synaptic dysfunction and behavioral deficits

We report the development of a novel, aqueous-soluble, safe, small molecule, experimental therapeutic that suppresses injury-induced, proinflammatory cytokine increases in the brain, with resultant attenuation of synaptic protein biomarker loss and improvement in hippocampus-dependent behavioral deficits. A GMP production scheme for the active pharmaceutical ingredient, compound 17, is presented. The development and large-scale availability of this novel compound allow exploration of new, potentially disease-modifying, therapeutic approaches to CNS disorders.

New, simple and versatile synthesis of 4,6-disubstituted pyridazin-3(2H)-ones

A simple, two-step synthesis of 4,6-disubstituted pyridazin-3(2H)-ones starting from 2-diethoxyphosphoryl-4-oxoalkanoates and hydrazines is described. The intermediate 4-diethoxyphosphoryl-4,5-dihydropyridazin-3(2H)-ones obtained in this way are used in a

COMPOSITIONS AND TREATMENTS USING PYRIDAZINE COMPOUNDS AND CHOLINESTERASE INHIBITORS

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